Endocardial fibroelastosis and dilated cardiomyopathy - the past and future of the interface between histology and genetics

• Published in: Romanian journal of morphology and embryology Vol. 61; no. 4; pp. 999 - 1005
• Main Authors: Luca, Alina Costina, Lozneanu, Ludmila, Miron, Ingrith Crenguţa, Trandafir, Laura Mihaela, Cojocaru, Elena, Pădureţ, Ioana Alexandra, Mihăilă, Doina, Leon-Constantin, Maria Magdalena, Chiriac, Ştefan, Iordache, Alin Constantin, Ţarcă, Elena
• Format: Journal Article
• Language: English
• Published: Romania Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 01.10.2020
• Subjects: Cardiomyopathy, Dilated - genetics; Child; Collagen; Endocardial Fibroelastosis - genetics; Endocardium; Heart Ventricles; Humans; Infant, Newborn; Review

Endocardial fibroelastosis (EFE) signifies the pathological process by which collagen and elastin are focally or diffuse deposited in the endocardium of the left ventricle. The new layer causes left ventricular dysfunction sometimes with fulminant progression to heart failure. EFE is a major compone...