Insecticidal Properties of Annonaceous Acetogenins and Their Analogues. Interaction with Lipid Membranes

• Published in: Natural product communications Vol. 7; no. 9; pp. 1215 - 1218
• Main Authors: Blessing, Lilian Di Toto, Ramos, Juan, Diaz, Sonia, Altabef, Aída Ben, Bardón, Alicia, Brovetto, Margarita, Seoane, Gustavo, Neske, Adriana
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 01.09.2012
• Subjects: Acetogenins - chemistry; Acetogenins - pharmacology; Animals; Calorimetry, Differential Scanning; Insecticides - chemistry; Insecticides - pharmacology; Membrane Lipids - chemistry; Spectroscopy, Fourier Transform Infrared; Spodoptera; Annonaceous acetogenins; DSC; Toxicity; FTIR; POPC

The interactions were studied by FTIR and DSC of the terminal lactone of annonaceous acetogenins (ACGs) and synthetic analogues, such as THF, with POPC bilayers, as well as the toxic effect produced by these compounds on Spodoptera frugiperda larvae. The aim of this work was to find a relationship b...