Randomized, double-blinded, placebo controlled study to assess the effect of topical 1% nicotinamide on actinic keratoses
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| Published in | British journal of dermatology (1951) Vol. 162; no. 5; pp. 1138 - 1139 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
Oxford, UK
Blackwell Publishing Ltd
01.05.2010
Wiley-Blackwell |
| Subjects | |
| Online Access | Get full text |
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| Author | Damian, D. Radojkovic, B. Vestergaard, M. Moloney, F. |
|---|---|
| Author_xml | – sequence: 1 givenname: F. surname: Moloney fullname: Moloney, F. organization: Discipline of Dermatology, University of Sydney,Sydney Cancer Center – sequence: 2 givenname: M. surname: Vestergaard fullname: Vestergaard, M. organization: Department of Dermatology – sequence: 3 givenname: B. surname: Radojkovic fullname: Radojkovic, B. organization: Department of Pharmacy – sequence: 4 givenname: D. surname: Damian fullname: Damian, D. organization: Discipline of Dermatology, University of Sydney,Sydney Cancer Center |
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| Copyright | 2010 The Authors. Journal Compilation © 2010 British Association of Dermatologists 2015 INIST-CNRS |
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| Issue | 5 |
| Keywords | Skin disease Premalignant lesion Dermatology niacinamide Malignant tumor precancers Skin cancer Local administration Immunosuppression Double blind study Nicotinamide ultraviolet immunosuppression Cancer Keratosis |
| Language | English |
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| Notes | istex:A99F9601BA35BD2893D5365ABF3089D2929DF0A3 ark:/67375/WNG-T5RH97J3-W ArticleID:BJD9659 Conflicts of interest: the authors have no conflict of interest to declare. SourceType-Other Sources-1 ObjectType-Correspondence-1 ObjectType-News-2 content type line 66 ObjectType-Article-3 |
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| PublicationDate | May 2010 |
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| PublicationTitle | British journal of dermatology (1951) |
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| PublicationYear | 2010 |
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| References | Gensler HL. Prevention of photoimmunosuppression and photocarcinogenesis by topical nicotinamide. Nutr Cancer 1997; 29:157-62. Damian DL, Patterson CRS, Stapelberg M et al. Ultraviolet radiation-induced immunosuppression is greater in men and prevented by topical nicotinamide. J Invest Dermatol 2008; 128:447-54. Criscione VD, Weinstock MA, Naylor MF et al. Actinic keratoses: natural history and risk of malignant transformation in the Veterans Affairs Topical Tretinoin Chemoprevention Trial Group. Cancer 2009; 115:2523-30. Hiramoto K, Tanaka H, Yanagihara N et al. Effect of 17 beta-estradiol on immunosuppression induced by ultraviolet B irradiation. Arch Dermatol Res 2004; 295:307-11. Thompson SC, Jolley D, Marks R. Reduction of solar keratoses by regular sunscreen use. N Engl J Med 1993; 329:1147-51. Moloney FJ, Comber H, O'Lorcain P et al. A population-based study of skin cancer incidence and prevalence in renal transplant recipients. Br J Dermatol 2006; 154:498-504. Sivapirabu G, Yiasemides E, Halliday GM et al. Topical nicotinamide modulates cellular energy metabolism and provides broad-spectrum protection against ultraviolet radiation-induced immunosuppression in humans. Br J Dermatol 2009; 161:1357-64. Roewert-Huber J, Stockfleth E, Kerl H. Pathology and pathobiology of actinic (solar) keratosis - an update. Br J Dermatol 2007; 157:18-20. Magni G, Amici A, Emanuelli M et al. Enzymology of NAD+ homeostasis in man. Cell Mol Life Sci 2004; 61:19-34. Svobodova A, Zdarilova A, Maliskova J et al. Attenuation of UVA-induced damage to human keratinocytes by silymarin. J Dermatol Sci 2007; 46:21-30. 1997; 29 2006; 154 2007; 157 2008; 128 2009; 161 2004; 61 1993; 329 2007; 46 2004; 295 2009; 115 |
| References_xml | – volume: 157 start-page: 18 year: 2007 end-page: 20 article-title: Pathology and pathobiology of actinic (solar) keratosis – an update publication-title: Br J Dermatol – volume: 128 start-page: 447 year: 2008 end-page: 54 article-title: Ultraviolet radiation‐induced immunosuppression is greater in men and prevented by topical nicotinamide publication-title: J Invest Dermatol – volume: 29 start-page: 157 year: 1997 end-page: 62 article-title: Prevention of photoimmunosuppression and photocarcinogenesis by topical nicotinamide publication-title: Nutr Cancer – volume: 329 start-page: 1147 year: 1993 end-page: 51 article-title: Reduction of solar keratoses by regular sunscreen use publication-title: N Engl J Med – volume: 295 start-page: 307 year: 2004 end-page: 11 article-title: Effect of 17 beta‐estradiol on immunosuppression induced by ultraviolet B irradiation publication-title: Arch Dermatol Res – volume: 161 start-page: 1357 year: 2009 end-page: 64 article-title: Topical nicotinamide modulates cellular energy metabolism and provides broad‐spectrum protection against ultraviolet radiation‐induced immunosuppression in humans publication-title: Br J Dermatol – volume: 154 start-page: 498 year: 2006 end-page: 504 article-title: A population‐based study of skin cancer incidence and prevalence in renal transplant recipients publication-title: Br J Dermatol – volume: 115 start-page: 2523 year: 2009 end-page: 30 article-title: Actinic keratoses: natural history and risk of malignant transformation in the Veterans Affairs Topical Tretinoin Chemoprevention Trial Group publication-title: Cancer – volume: 61 start-page: 19 year: 2004 end-page: 34 article-title: Enzymology of NAD+ homeostasis in man publication-title: Cell Mol Life Sci – volume: 46 start-page: 21 year: 2007 end-page: 30 article-title: Attenuation of UVA‐induced damage to human keratinocytes by silymarin publication-title: J Dermatol Sci |
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| SubjectTerms | Aged Aged, 80 and over Biological and medical sciences Dermatology Double-Blind Method Female Follow-Up Studies Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Keratosis, Actinic - drug therapy Male Medical sciences Middle Aged niacinamide Niacinamide - therapeutic use precancers skin cancer Tissue, organ and graft immunology Treatment Outcome Tumors of the skin and soft tissue. Premalignant lesions ultraviolet immunosuppression Vitamin B Complex - therapeutic use |
| Title | Randomized, double-blinded, placebo controlled study to assess the effect of topical 1% nicotinamide on actinic keratoses |
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