A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis
In normal epidermis, beta1 integrin expression is confined to the basal layer, whereas in hyperproliferative epidermis, integrins are also expressed in the suprabasal layers. Transgenic mice in which integrins are expressed suprabasally via the involucrin promoter have a sporadic psoriatic phenotype...
Saved in:
Published in | The Journal of clinical investigation Vol. 108; no. 4; pp. 527 - 536 |
---|---|
Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
American Society for Clinical Investigation
15.08.2001
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Be the first to leave a comment!