In Vitro and In Vivo Evaluation of Starfish Bone-Derived β-Tricalcium Phosphate as a Bone Substitute Material

• Published in: Materials Vol. 12; no. 11; p. 1881
• Main Authors: Ishida, Haruka, Haniu, Hisao, Takeuchi, Akari, Ueda, Katsuya, Sano, Mahoko, Tanaka, Manabu, Takizawa, Takashi, Sobajima, Atsushi, Kamanaka, Takayuki, Saito, Naoto
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 11.06.2019; MDPI
• Subjects: Adsorption; angiogenesis; Aqueous solutions; Biocompatibility; Biomedical materials; bone substitute; Calcium carbonate; Calcium phosphates; Cell growth; Communication; Experiments; FDA approval; In vivo methods and tests; Laboratory animals; Materials substitution; Methods; Pore size; Porosity; porous calcium phosphate; Scanning electron microscopy; Skin & tissue grafts; starfish; Substitute bone; β-tricalcium phosphate; United States > US; Japan; Germany; bone substitute; β-tricalcium phosphate; calcium carbonate; starfish; angiogenesis; porous calcium phosphate

We evaluated starfish-derived β-tricalcium phosphate (Sf-TCP) obtained by phosphatization of starfish-bone-derived porous calcium carbonate as a potential bone substitute material. The Sf-TCP had a communicating pore structure with a pore size of approximately 10 μm. Although the porosity of Sf-TCP...