Disruption of social circadian rhythms in major depression: A preliminary report
While dysregulations of physiological circadian rhythms are common findings in depression and have been posited to be involved in the mediation of depressive episodes, only recently has the role of social circadian rhythms in the pathogenesis of depression been a focus of interest. The Social Rhythm...
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Published in | Psychiatry research Vol. 42; no. 3; pp. 221 - 230 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Shannon
Elsevier Ireland Ltd
01.06.1992
Elsevier |
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Abstract | While dysregulations of physiological circadian rhythms are common findings in depression and have been posited to be involved in the mediation of depressive episodes, only recently has the role of social circadian rhythms in the pathogenesis of depression been a focus of interest. The Social Rhythm Metric (SRM), designed to describe the regularity of a human subject's social circadian rhythms, was used in this study to compare the social rhythms of depressed patients with those of normal controls and to determine the relationship between SRM scores and depression severity. Depressed patients' SRM scores were significantly lower than those of normal controls. The SRM negatively correlated with scores on the Hamilton Rating Scale for Depression. Overall social activity was negatively correlated with a Hamilton item, social activity impairment. The results of this preliminary study support the hypothesis that social zeitgebers are disrupted in major depression. |
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AbstractList | While dysregulations of physiological circadian rhythms are common findings in depression and have been posited to be involved in the mediation of depressive episodes, only recently has the role of social circadian rhythms in the pathogenesis of depression been a focus of interest. The Social Rhythm Metric (SRM), designed to describe the regularity of a human subject's social circadian rhythms, was used in this study to compare the social rhythms of depressed patients with those of normal controls and to determine the relationship between SRM scores and depression severity. Depressed patients' SRM scores were significantly lower than those of normal controls. The SRM negatively correlated with scores on the Hamilton Rating Scale for Depression. Overall social activity was negatively correlated with a Hamilton item, social activity impairment. The results of this preliminary study support the hypothesis that social zeitgebers are disrupted in major depression. |
Author | Yager, Alison Baxter, Lewis R. Szuba, Martin P. Allen, Eva M. Guze, Barry H. |
Author_xml | – sequence: 1 givenname: Martin P. surname: Szuba fullname: Szuba, Martin P. organization: Martin P. Szuba, M.D., is Assistant Professor, Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA., USA – sequence: 2 givenname: Alison surname: Yager fullname: Yager, Alison organization: Alison Yager is a student at Brown University, Providence, RI., USA – sequence: 3 givenname: Barry H. surname: Guze fullname: Guze, Barry H. organization: Barry H. Guze, M.D., is Assistant Professor, Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA., USA – sequence: 4 givenname: Eva M. surname: Allen fullname: Allen, Eva M. organization: Eva M. Allen is Research Assistant, UCLA Neuropsychiatric Institute, Los Angeles, CA., USA – sequence: 5 givenname: Lewis R. surname: Baxter fullname: Baxter, Lewis R. organization: Lewis R. Baxter, Jr., M.D., is Associate Professor, Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, CA., USA |
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Keywords | Affective disorder diurnal mood zeitgebers Social Rhythm Metric Human Mood disorder Social behavior Social Rhythm Metrics Ehlers et al Evaluation scale Pathogenesis Daily living Depression Biological rhythm Circadian rhythm |
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Snippet | While dysregulations of physiological circadian rhythms are common findings in depression and have been posited to be involved in the mediation of depressive... |
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SubjectTerms | Activities of Daily Living - psychology Adult Adult and adolescent clinical studies Affective disorder Biological and medical sciences Circadian Rhythm Depressive Disorder - diagnosis Depressive Disorder - psychology diurnal mood Female Hospitalization Humans Male Medical sciences Mood disorders Personality Assessment Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Social Behavior Social Environment Social Rhythm Metric zeitgebers |
Title | Disruption of social circadian rhythms in major depression: A preliminary report |
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