Comparison of choroidal thickness in patients with active and stable thyroid eye disease

• Published in: Arquivos brasileiros de oftalmologia Vol. 82; no. 2; pp. 124 - 128
• Main Authors: Gul, Adem, Basural, Ekrem, Ozturk, Hilal Eser
• Format: Journal Article
• Language: English; Portuguese
• Published: Brazil Conselho Brasileiro de Oftalmologia 01.03.2019
• Subjects: Adolescent; Adult; Choroid - diagnostic imaging; Choroid - pathology; Female; Graves Ophthalmopathy - diagnostic imaging; Graves Ophthalmopathy - pathology; Humans; Macula Lutea - pathology; Male; Middle Aged; OPHTHALMOLOGY; Organ Size; Prospective Studies; Reference Values; Tomography, Optical Coherence - methods; Young Adult; Coroide/anatomia & his to logia; Choroid/anatomy & histology; Oftalmopatia de Graves; Tomografia de coerência óptica; Tomography, optical coherence; Graves ophthalmopathy
• DOI: 10.5935/0004-2749.20190019
• ISSN: 0004-2749; 1678-2925

To compare the choroidal thickness in active and stable phases of thyroid eye disease. Forty-seven eyes of 47 patients with thyroid eye disease were prospectively studied. Patients were evaluated on the basis of their clinical activity scores, with scores 33 defined as active disease. Subfoveal, temporal macular, nasal macular, temporal peripapillary, and nasal peripapillary choroidal thickness measurements were performed with Cirrus enhanced depth imaging spectral-domain optical coherence tomography, and the results in the two groups were compared. Twenty-four patients were int he active group, whereas 23 patients were in the stable group. Choroidal thickness was significantly higher in the subfoveal and temporal macular regions in the active group. Although the nasal macular and peripapillary values were also higher in the active group, the difference was insignificant. Subfoveal choroidal thickness was significantly higher in patients with thyroid eye disease in the active phase than in those with stable phase disease.