Heparin treatment and resolution of left ventricular thrombosis

In a 70-year-old man admitted to our hospital because of repeated episodes of transient disorientation, an ECG showed a recent inferior myocardial infarction. A two-dimensional echocardiography detected hypo-akinesia in the apex region, where a hyperechogenic oval and pedunculated mass with a maximu...

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Published inInternational journal of cardiology Vol. 43; no. 3; pp. 338 - 340
Main Authors Palazzuoli, Vincenzo, Mondillo, Sergio, D'Aprile, Nicola, Faglia, Sebastiano, Palazzuoli, Alberto
Format Journal Article
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 01.03.1994
Elsevier Science
Subjects
Aged
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Echocardiography
Electrocardiography
Heart Diseases - diagnostic imaging
Heart Diseases - drug therapy
Heart Ventricles
Heparin
Heparin - administration & dosage
Heparin - therapeutic use
Humans
Ischemic Attack, Transient - etiology
Male
Medical sciences
Myocardial infarction
Myocardial Infarction - complications
Pharmacology. Drug treatments
Thrombosis - diagnostic imaging
Thrombosis - drug therapy
Ventricular thrombosis
Myocardial infarction
Ventricular thrombosis
Heparin
Human
Case study
Chemotherapy
Treatment
Heart disease
Cardiovascular disease
Anticoagulant
Thrombosis
Elderly
Left ventricle
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Abstract In a 70-year-old man admitted to our hospital because of repeated episodes of transient disorientation, an ECG showed a recent inferior myocardial infarction. A two-dimensional echocardiography detected hypo-akinesia in the apex region, where a hyperechogenic oval and pedunculated mass with a maximun diameter of 1.5 cm, attributable to an organized thrombus, was located. After 20 days of therapy with calcium-heparin at a dose of 12 500 IU every 8 h, a two-dimensional echocardiography showed the complete disappearance of the mass. This and other recent reports confirm the thrombolytic activity of the drug and the possibility of postponing the immediate surgical removal of intraventricular thrombi in favour of heparin treatment.
AbstractList In a 70-year-old man admitted to our hospital because of repeated episodes of transient disorientation, an ECG showed a recent inferior myocardial infarction. A two-dimensional echocardiography detected hypo-akinesia in the apex region, where a hyperechogenic oval and pedunculated mass with a maximun diameter of 1.5 cm, attributable to an organized thrombus, was located. After 20 days of therapy with calcium-heparin at a dose of 12 500 IU every 8 h, a two-dimensional echocardiography showed the complete disappearance of the mass. This and other recent reports confirm the thrombolytic activity of the drug and the possibility of postponing the immediate surgical removal of intraventricular thrombi in favour of heparin treatment.
In a 70-year-old man admitted to our hospital because of repeated episodes of transient disorientation, an ECG showed a recent inferior myocardial infarction. A two-dimensional echocardiography detected hypo-akinesia in the apex region, where a hyperechogenic oval and pedunculated mass with a maximum diameter of 1.5 cm, attributable to an organized thrombus, was located. After 20 days of therapy with calcium-heparin at a dose of 12,500 IU every 8 h, a two-dimensional echocardiography showed the complete disappearance of the mass. This and other recent reports confirm the thrombolytic activity of the drug and the possibility of postponing the immediate surgical removal of intraventricular thrombi in favour of heparin treatment.
Author Faglia, Sebastiano
Palazzuoli, Alberto
Palazzuoli, Vincenzo
D'Aprile, Nicola
Mondillo, Sergio
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Issue 3
Keywords Myocardial infarction
Ventricular thrombosis
Heparin
Human
Case study
Chemotherapy
Treatment
Heart disease
Cardiovascular disease
Anticoagulant
Thrombosis
Elderly
Left ventricle
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Elsevier Science
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Peteiro, Gomez (BIB2) 1992; 126
Edelberg, Pizzo (BIB4) 1990; 29
Leor, Agranat, Mohr, Kaplimsky, Motro (BIB5) 1990; 119
Butman (10.1016/0167-5273(94)90217-8_BIB1) 1991; 122
Edelberg (10.1016/0167-5273(94)90217-8_BIB4) 1990; 29
Keren (10.1016/0167-5273(94)90217-8_BIB3) 1987; 60
Leor (10.1016/0167-5273(94)90217-8_BIB5) 1990; 119
Peteiro (10.1016/0167-5273(94)90217-8_BIB2) 1992; 126
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  contributor:
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SubjectTerms Aged
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Echocardiography
Electrocardiography
Heart Diseases - diagnostic imaging
Heart Diseases - drug therapy
Heart Ventricles
Heparin
Heparin - administration & dosage
Heparin - therapeutic use
Humans
Ischemic Attack, Transient - etiology
Male
Medical sciences
Myocardial infarction
Myocardial Infarction - complications
Pharmacology. Drug treatments
Thrombosis - diagnostic imaging
Thrombosis - drug therapy
Ventricular thrombosis
Title Heparin treatment and resolution of left ventricular thrombosis
URI https://dx.doi.org/10.1016/0167-5273(94)90217-8
https://www.ncbi.nlm.nih.gov/pubmed/8181893
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