Hemogram index parameters in the evaluation of male breast cancer and inflammatory response: a case-control study
Our aim was to investigate the hemogram index parameters and their clinical significance in the evaluation of the inflammatory response of patients with male breast cancer, who are rarely observed in the literature. In total, 22 (n=22) healthy male and 28 (n=28) male breast cancer patients without s...
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Published in | Revista da Associacao Medica Brasileira (1992) Vol. 68; no. 1; pp. 94 - 99 |
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Main Authors | , , , , , , , |
Format | Magazine Article |
Language | English |
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01.01.2022
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Abstract | Our aim was to investigate the hemogram index parameters and their clinical significance in the evaluation of the inflammatory response of patients with male breast cancer, who are rarely observed in the literature.
In total, 22 (n=22) healthy male and 28 (n=28) male breast cancer patients without synchronous/metachronous tumors were included in this study. They were grouped as the healthy male control group (Group 1) and the male breast cancer patient group (Group 2). The male breast cancer was divided into two subgroups, namely, early stage [(stage: 0/I/II) (Group 2A)] and late stage [(stage: III/IV) (Group 2B)], and their hemogram index parameters were compared.
A significant (p>0.05) increase was observed in neutrophil/lymphocyte ratio (NLR) and·platelet/lymphocyte ratio (PLR) values in the late stage (Group 2B: stage III/IV) compared to the early stage (Group 2A: stage 0/I/II) and healthy control (Group 1) groups.
In male breast cancer patients, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio values were significantly higher as the stage of cancer increased. These readily available simple tests can be used to evaluate the host's inflammatory response in male breast cancer. |
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AbstractList | Our aim was to investigate the hemogram index parameters and their clinical significance in the evaluation of the inflammatory response of patients with male breast cancer, who are rarely observed in the literature.
In total, 22 (n=22) healthy male and 28 (n=28) male breast cancer patients without synchronous/metachronous tumors were included in this study. They were grouped as the healthy male control group (Group 1) and the male breast cancer patient group (Group 2). The male breast cancer was divided into two subgroups, namely, early stage [(stage: 0/I/II) (Group 2A)] and late stage [(stage: III/IV) (Group 2B)], and their hemogram index parameters were compared.
A significant (p>0.05) increase was observed in neutrophil/lymphocyte ratio (NLR) and·platelet/lymphocyte ratio (PLR) values in the late stage (Group 2B: stage III/IV) compared to the early stage (Group 2A: stage 0/I/II) and healthy control (Group 1) groups.
In male breast cancer patients, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio values were significantly higher as the stage of cancer increased. These readily available simple tests can be used to evaluate the host's inflammatory response in male breast cancer. |
Author | Dal, Fatih Havare, Semiha Battal Ferlengez, Ekrem Sari, Serkan Çolak, Şükrü Ökmen, Hasan Ulusan, Kıvılcım Orhan, Bağnu |
Author_xml | – sequence: 1 givenname: Fatih orcidid: 0000-0002-9768-8125 surname: Dal fullname: Dal, Fatih organization: Ministry of health, Istanbul Training and Research Hospital, Department of General Surgery - Istanbul, Turkey – sequence: 2 givenname: Hasan orcidid: 0000-0002-2297-3386 surname: Ökmen fullname: Ökmen, Hasan organization: Ministry of health, Istanbul Training and Research Hospital, Department of General Surgery - Istanbul, Turkey – sequence: 3 givenname: Kıvılcım orcidid: 0000-0002-4793-5714 surname: Ulusan fullname: Ulusan, Kıvılcım organization: Ministry of health, Istanbul Training and Research Hospital, Department of General Surgery - Istanbul, Turkey – sequence: 4 givenname: Semiha Battal orcidid: 0000-0003-4822-4989 surname: Havare fullname: Havare, Semiha Battal organization: Ministry of health, Istanbul Training and Research Hospital, Department of Medical Pathology - Istanbul, Turkey – sequence: 5 givenname: Bağnu orcidid: 0000-0003-1779-7784 surname: Orhan fullname: Orhan, Bağnu organization: Ministry of health, Istanbul Training and Research Hospital, Department of Medical Biochemistry - Istanbul, Turkey – sequence: 6 givenname: Şükrü orcidid: 0000-0002-7394-3320 surname: Çolak fullname: Çolak, Şükrü organization: Ministry of health, Istanbul Training and Research Hospital, Department of General Surgery - Istanbul, Turkey – sequence: 7 givenname: Ekrem orcidid: 0000-0002-9714-2421 surname: Ferlengez fullname: Ferlengez, Ekrem organization: Ministry of health, Istanbul Training and Research Hospital, Department of General Surgery - Istanbul, Turkey – sequence: 8 givenname: Serkan orcidid: 0000-0003-2918-1776 surname: Sari fullname: Sari, Serkan organization: Ministry of health, Istanbul Training and Research Hospital, Department of General Surgery - Istanbul, Turkey |
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SubjectTerms | Blood Cell Count Breast Neoplasms, Male - diagnostic imaging Breast Neoplasms, Male - pathology Case-Control Studies Humans Lymphocytes - pathology Male Neutrophils Retrospective Studies |
Title | Hemogram index parameters in the evaluation of male breast cancer and inflammatory response: a case-control study |
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