Cross-reactivity between murine melanoma antigen B700 and a human melanoma-associated antigen (M-66) recognized by autologous antibody: evidence suggesting shared epitopes

• Published in: Biochimica et biophysica acta Vol. 1182; no. 1; pp. 51 - 56
• Main Authors: Toporowicz, A, Gersten, D M, Hearing, V J, Brown, W E, Vlock, D R
• Format: Journal Article
• Language: English
• Published: Netherlands 04.08.1993
• Subjects: Animals; Antibodies - chemistry; Antigens, Neoplasm - chemistry; Cell Line; Cross Reactions; Epitopes - analysis; Humans; Melanoma - immunology; Melanoma-Specific Antigens; Mice; Neoplasm Proteins - chemistry

We have previously reported the purification and partial characterization of a human melanoma-associated antigen (M-66) recognized by autologous antibody. This antigen was found to be an unusually acidic 66 kDa glycoprotein. In studies of murine melanoma, a 67-kDa albumin-like melanoma-associated an...