Biofilm-forming ability and adherence to poly-(methyl-methacrylate) acrylic resin materials of oral Candida albicans strains isolated from HIV positive subjects

• Published in: The journal of advanced prosthodontics Vol. 6; no. 1; pp. 30 - 34
• Main Authors: Uzunoglu, Emel, Yildirim Bicer, Arzu Zeynep, Dolapci, Istar, Dogan, Arife
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Academy of Prosthodontics 01.02.2014; 대한치과보철학회
• Subjects: Original; 치의학; Candida albicans; Biofilms; PMMA; Adhesion assay
• ISSN: 2005-7806; 2005-7814
• DOI: 10.4047/jap.2014.6.1.30

This study evaluated the adhesion to acrylic resin specimens and biofilm formation capability of Candida albicans strains isolated from HIV positive subjects' oral rinse solutions. The material tested was a heat-cured acrylic resin (Acron Duo). Using the adhesion and crystal violet assays, 14 oral Candida albicans isolated from HIV-positive subjects and 2 references Candida strains (C. albicans ATCC 90028 and C. albicans ATCC 90128) were compared for their biofilm production and adhesion properties to acrylic surfaces in vitro. There were no significant differences in adhesion (P=.52) and biofilm formation assays (P=.42) by statistical analysis with Mann-Whitney test. Denture stomatitis and increased prevalence of candidal carriage in HIV infected patients is unlikely to be related to the biofilm formation and adhesion abilities of C. albicans to acrylic resin materials.