A randomized trial of ofloxacin versus cefoxitin and doxycycline in the outpatient treatment of acute salpingitis

• Published in: American journal of obstetrics and gynecology Vol. 164; no. 5 Pt 2; p. 1390
• Main Authors: Wendel, Jr, G D, Cox, S M, Bawdon, R E, Theriot, S K, Heard, M C, Nobles, B J
• Format: Journal Article
• Language: English
• Published: United States 01.05.1991
• Subjects: Acute Disease; Adult; Ambulatory Care; Cefoxitin - adverse effects; Cefoxitin - therapeutic use; Chi-Square Distribution; Chlamydia Infections - drug therapy; Chlamydia Infections - microbiology; Chlamydia trachomatis; Doxycycline - adverse effects; Doxycycline - therapeutic use; Drug Therapy, Combination - adverse effects; Drug Therapy, Combination - therapeutic use; Female; Gonorrhea - drug therapy; Gonorrhea - microbiology; Humans; Ofloxacin - adverse effects; Ofloxacin - therapeutic use; Probenecid - therapeutic use; Salpingitis - drug therapy; Salpingitis - microbiology

The object of this randomized study was to compare the safety and efficacy of oral ofloxacin, 400 mg twice daily for 10 days, versus intramuscular cefoxitin, 2 gm, plus oral probenecid, 1 gm, followed by oral doxycycline, 100 mg twice daily for 10 days, in the outpatient treatment of uncomplicated a...