The dendritic tree and brain disorders

• Published in: Molecular and cellular neuroscience Vol. 50; no. 1; pp. 10 - 20
• Main Authors: Kulkarni, Vaishali A., Firestein, Bonnie L.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2012
• Subjects: Animals; Axons - metabolism; Axons - pathology; Brain; Brain - growth & development; Brain - pathology; Cytoskeleton; Cytoskeleton - metabolism; Dendrites - metabolism; Dendrites - pathology; Dendritic branching; Dendritic spines; Humans; Mental disorders; Mental Disorders - pathology; Mice; Morphogenesis; Nervous system; Nervous System Diseases - pathology; Neurons; Plasticity (dendritic); Plasticity (synaptic); Synapses; Synapses - metabolism; Synapses - pathology
• ISSN: 1044-7431; 1095-9327; 1095-9327
• DOI: 10.1016/j.mcn.2012.03.005

Dendrite morphogenesis is a complex but well-orchestrated process and includes the development of dendritic branches, forming characteristic dendrite arbors, and dendritic spines, allowing neurons to communicate with each other. Various studies report that many neuropsychiatric disorders are charact...