Post-mortem stability of membrane-associated sialidase activity in brain

• Published in: Neuroscience letters Vol. 107; no. 1-3; p. 267
• Main Authors: Leskawa, K C, Szoke, M, Malone, M J
• Format: Journal Article
• Language: English
• Published: Ireland 15.12.1989
• Subjects: Animals; Brain - enzymology; Male; Neuraminidase - metabolism; Postmortem Changes; Rats; Rats, Inbred Strains; Substrate Specificity

The post-mortem changes in membrane-associated sialidase (N-acetylneuraminosyl glycohydrolase, EC 3.2.1.18) were examined in rat brain obtained and stored in a manner which paralleled neuropathological handling of human brains. When whole brains were held at 4 degrees C in covered containers for var...