Prevalence of anti-Leishmania donovani antibody among Brazilian blood donors and multiply transfused hemodialysis patients

• Published in: The American journal of tropical medicine and hygiene Vol. 57; no. 2; p. 168
• Main Authors: Luz, K G, da Silva, V O, Gomes, E M, Machado, F C, Araujo, M A, Fonseca, H E, Freire, T C, d'Almeida, J B, Palatnik, M, Palatnik-de Sousa, C B
• Format: Journal Article
• Language: English
• Published: United States 01.08.1997
• Subjects: Animals; Antibodies, Protozoan - analysis; Blood Donors; Bone Marrow - parasitology; Brazil - epidemiology; Enzyme-Linked Immunosorbent Assay - methods; Humans; Leishmania donovani - immunology; Leishmaniasis, Visceral - diagnosis; Leishmaniasis, Visceral - epidemiology; Leishmaniasis, Visceral - immunology; Liver - parasitology; Prevalence; Psychodidae - parasitology; Renal Dialysis - adverse effects; Risk Factors; Sensitivity and Specificity; Seroepidemiologic Studies; Spleen - parasitology; Transfusion Reaction

The prevalence of anti-Leishmania donovani antibodies was investigated in 1,500 Brazilian blood donors and multiply transfused hemodialysis patients. Sera were tested using the fucose-mannose ligand (FML) ELISA, which was shown to have 100% sensitivity and 96% specificity for kala-azar. Among 1,194...