Interactions of fluoroquinolone antibiotics with sodium hypochlorite in bromide-containing synthetic water: Reaction kinetics and transformation pathways

• Published in: Journal of environmental sciences (China) Vol. 102; pp. 170 - 184
• Main Authors: Pan, Zihan, Zhu, Yunjie, Wei, Min, Zhang, Yuanyuan, Yu, Kefu
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.04.2021
• Subjects: Anti-Bacterial Agents; aquatic organisms; Bioaccumulation; Br-DBPs; Bromides; bromination; bromine; China; chlorination; chlorine; Chromatography, Liquid; ciprofloxacin; dealkylation; decarboxylation; density functional theory; Disinfection; enrofloxacin; flumequine; Fluoroquinolones; FQs; Halogenation; humic acids; Kinetics; liquid chromatography; lomefloxacin; mariculture; Marine aquaculture water; moieties; NaClO; norfloxacin; ofloxacin; oxidation; piperazine; reaction kinetics; secondary amines; Sodium Hypochlorite; sulfates; Tandem Mass Spectrometry; Water; Water Pollutants, Chemical - analysis; Water Purification; China; Marine aquaculture water; FQs; Br-DBPs; NaClO; Bioaccumulation

Seven popular fluoroquinolone antibiotics (FQs) in synthetic marine aquaculture water were subject to sodium hypochlorite (NaClO) disinfection scenario to investigate their reaction kinetics and transformation during chlorination. Reactivity of each FQ to NaClO was following the order of ofloxacin (...