Functional comparison of the transposition core machineries of phage Mu and Haemophilus influenzae Mu-like prophage Hin–Mu reveals interchangeable components

• Published in: Virology (New York, N.Y.) Vol. 331; no. 1; pp. 6 - 19
• Main Authors: Saariaho, Anna-Helena, Lamberg, Arja, Elo, Seija, Savilahti, Harri
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 05.01.2005
• Subjects: Amino Acid Sequence; Bacteriophage Mu; Bacteriophage mu - chemistry; Bacteriophage mu - genetics; Base Sequence; Binding Sites; Catalysis; Deoxyribonuclease I - chemistry; DNA Footprinting; DNA Transposable Elements; DNA, Viral - chemistry; DNase I footprinting; Genome, Viral; Haemophilus influenzae; Haemophilus influenzae - genetics; Haemophilus influenzae - virology; In vitro DNA transposition; Molecular Sequence Data; MuA transposase; Phage Mu; Prophage; Prophages - chemistry; Prophages - genetics; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Transposases - chemistry; Transposases - genetics; Bacteriophage Mu; Prophage; In vitro DNA transposition; DNase I footprinting; MuA transposase

Bacteriophage Mu uses DNA transposition for propagation and is a model for transposition studies in general. Recent identification of Mu-like prophages within bacterial genomes offers new material for evolutionary and comparative functional studies. One such prophage, Hin–Mu of Haemophilus influenza...