Distribution and biosynthesis of aminopeptidase n and dipeptidyl aminopeptidase IV in rat small intestine

• Published in: Biochimica et biophysica acta Vol. 761; no. 1; pp. 66 - 75
• Main Authors: Miura, Soichiro, Song, In-Sung, Morita, Akira, Erickson, Roger H., Kim, Young S.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 22.11.1983; Elsevier; North-Holland
• Subjects: Aminopeptidase N; Aminopeptidases - isolation & purification; Aminopeptidases - metabolism; Analytical, structural and metabolic biochemistry; Animals; Biological and medical sciences; CD13 Antigens; Cytosol - enzymology; Dipeptidyl aminopeptidase IV; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - isolation & purification; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases - metabolism; Endopeptidases - metabolism; Enzyme distribuin; Enzymes and enzyme inhibitors; Fundamental and applied biological sciences. Psychology; Golgi Apparatus - enzymology; Hydrolases; Intestinal Mucosa - enzymology; Intestine, Small - enzymology; Male; Microvilli - enzymology; Radioimmunoassay; Rat small intestine; Rats; Rats, Inbred Strains; Dipeptidyl aminopeptidase IV; Rat small intestine; Radioimmunoassay; Aminopeptidase N; Enzyme distribuin; Peptidase; Rat; Enzyme; Rodentia; Biosynthesis; Small intestine; Golgi apparatus; Vertebrata; Brush border; Mammalia; Aminopeptidase (microsomal); Dipeptidyl peptidase I; Localization; Dipeptidyl peptidase II

The regional, cellular and subcellular distribution patterns of aminopeptidase N d dipeptidyl aminopeptidase IV were examined in rat small intestine. Aminopeptidyl N of brush border mebrane had maximal activity in the upper and middle intestine, while dipeptidyl aminopeptidaseV had a more uniform di...