Electrochemiluminescence of luminol enhanced by the synergetic catalysis of hemin and silver nanoparticles for sensitive protein detection

• Published in: Biosensors & bioelectronics Vol. 54; pp. 20 - 26
• Main Authors: Jiang, Xinya, Chai, Yaqin, Wang, Haijun, Yuan, Ruo
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier B.V 15.04.2014; Elsevier
• Subjects: Biological and medical sciences; Biosensing Techniques; Biotechnology; Carcinoembryonic Antigen - analysis; Catalysis; Electrochemical Techniques - methods; Electrochemiluminescence; Fundamental and applied biological sciences. Psychology; Glucose oxidase; Glucose Oxidase - metabolism; Graphene; Graphite - chemistry; Hemin; Hemin - chemistry; Humans; Hydrogen Peroxide - metabolism; Limit of Detection; Luminescent Agents - chemistry; Luminescent Measurements - methods; Luminol; Luminol - chemistry; Nanoparticles; Nanoparticles - chemistry; Silver - chemistry; Nanoparticles; Glucose oxidase; Hemin; Electrochemiluminescence; Graphene; Luminol; Enzyme; Nanoparticle; Protein; Silver; Oxidoreductases; Catalysis; Detection

A novel and ultrasensitive electrochemiluminescence (ECL) immunosensor, which was based on the amplifying ECL of luminol by hemin-reduced graphene oxide (hemin-rGO) and Ag nanoparticles (AgNPs) decorated reduced graphene oxide (Ag-rGO), was constructed for the detection of carcinoembryonic antigen (...