Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite

• Published in: Annals of internal medicine Vol. 141; no. 11; pp. 846 - 850
• Main Authors: Spiegel, Karine, Tasali, Esra, Penev, Plamen, Cauter, Eve Van
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA American College of Physicians 07.12.2004
• Subjects: Adult; Appetite - physiology; Biological and medical sciences; Clinical trials; Energy Metabolism; General aspects; Ghrelin; Humans; Hunger; Hunger - physiology; Leptin - blood; Male; Medical sciences; Men; Peptide Hormones - blood; Rodents; Sleep deprivation; Sleep Deprivation - blood; Sleep Deprivation - physiopathology; Starvation; Human; Appetite; Medicine; Hunger; Sleep; Healthy subject; Ghrelin; Leptin; Young adult; Male; Sleep wake cycle

Total sleep deprivation in rodents and in humans has been associated with hyperphagia. Over the past 40 years, self-reported sleep duration in the United States has decreased by almost 2 hours. To determine whether partial sleep curtailment, an increasingly prevalent behavior, alters appetite regula...