Functionalized HgTe nanoparticles promote laser-induced solid phase ionization/dissociation for comprehensive glycan sequencing

• Published in: Analyst (London) Vol. 141; no. 21; pp. 6093 - 6103
• Main Authors: Primadona, Indah, Lai, Yin-Hung, Capangpangan, Rey Y., Obena, Rofeamor P., Tseng, Mei-Chun, Huang, Ming-Feng, Chang, Huan-Tsung, Li, Shiou-Ting, Wu, Chung-Yi, Chien, Wei-Ting, Lin, Chun-Cheng, Wang, Yi-Sheng, Chen, Yu-Ju
• Format: Journal Article
• Language: English
• Published: England 01.01.2016
• Subjects: Biological effects; Glycan; Ionization; Lasers; Mass spectrometry; Mercury Compounds; Metal Nanoparticles; Nanoparticles; Nanostructure; Polysaccharides - analysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tellurium; Titanium dioxide

Glycoconjugates are ubiquitously present and play a critical role in various biological processes. Due to their low stability and incredibly high degree of structural diversity, the structural characterization of glycan generally requires chemical derivatization and sophisticated instrumentation. He...