Prednisone does not prevent recurrent fetal death in women with antiphospholipid antibody

• Published in: American journal of obstetrics and gynecology Vol. 160; no. 2; p. 439
• Main Authors: Lockshin, M D, Druzin, M L, Qamar, T
• Format: Journal Article
• Language: English
• Published: United States 01.02.1989
• Subjects: Aspirin - therapeutic use; Autoantibodies - analysis; Female; Fetal Death - prevention & control; Humans; Lupus Erythematosus, Systemic - drug therapy; Lupus Erythematosus, Systemic - immunology; Phospholipids - immunology; Prednisone - therapeutic use; Pregnancy; Pregnancy Complications - drug therapy; Pregnancy Complications - immunology; Prospective Studies; Recurrence

Effects of therapy, antibody titer, and pregnancy history on pregnancy outcome were evaluated in pregnancies of women with antiphospholipid antibody. Prior fetal death and a high antiphospholipid antibody titer (greater than 40 IgG phospholipid units) contributed independently, in an additive manner...