Improvement of eosinophilic chronic rhinosinusitis after infection with severe acute respiratory syndrome corona virus 2 during dupilumab therapy: A case report

• Published in: Frontiers in allergy Vol. 4; p. 1053777
• Main Authors: Koike-Ieki, Mariko, Kagoya, Ryoji, Toma-Hirano, Makiko, Sasajima, Yuko, Ito, Ken
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 02.02.2023
• Subjects: Allergy; cytokine balance; dupilumab; dysosmia; eosinophilic chronic rhinosinusitis; severe acute respiratory syndrome corona virus 2; severe acute respiratory syndrome corona virus 2; cytokine balance; dysosmia; eosinophilic chronic rhinosinusitis; dupilumab

Eosinophilic chronic rhinosinusitis (ECRS) is an intractable type 2 inflammatory disease of the paranasal sinuses that persists even after endoscopic sinus surgery (ESS) and systemic corticosteroid therapy. Dupilumab, a monoclonal antibody against the shared receptor components of interleukin (IL)-4...