Increased 1,2-diacylglycerol content in myopathic hamster hearts at a prenecrotic stage

• Published in: Life sciences (1973) Vol. 43; no. 17; p. 1371
• Main Authors: Okumura, K, Yamada, Y, Kondo, J, Ishida, A, Hashimoto, H, Ito, T, Ogawa, K, Kitoh, J
• Format: Journal Article
• Language: English
• Published: Netherlands 1988
• Subjects: Animals; Body Weight; Cardiomyopathies - metabolism; Cardiomyopathies - pathology; Chromatography, Thin Layer - methods; Cricetinae; Diglycerides - metabolism; Female; Glycerides - metabolism; Lipid Metabolism; Male; Mesocricetus; Myocardium - metabolism; Myocardium - pathology; Necrosis; Organ Size; Phospholipids - metabolism

1,2-Diacylglycerol (DAG) has been suggested to be a secondary messenger. In this study, we determined the amount of 1,2-DAG in heart tissue from Syrian hamsters with hereditary cardiomyopathy at 30 days (prenecrotic stage) and 90 days of age by thin-layer chromatography with flame ionization detecti...