miR-451 suppresses the NF-kappaB-mediated proinflammatory molecules expression through inhibiting LMP7 in diabetic nephropathy - Sun, Yan; Peng, Rui; Peng, Huimin; Liu, Handeng; Wen, Li; Wu, Tianhui; Yi, Hong; Li, Ailing; Zhang, Zheng (Molecular and cellular endocrinology, 2016)
Keywords: Animals; blood glucose; Cell Line; chromatin; Diabetes Mellitus, Experimental; Diabetic Nephropathies - metabolism; Diabetic nephropathy; Down-Regulation - physiology; excretion; gene expression regulation; glucose; Glucose - metabolism; high-throughput nucleotide sequencing; in situ hybridization; Inflammation; Inflammation - metabolism; Kidney - metabolism; Kidney Glomerulus - metabolism; kidneys; LMP7; Male; Mesangial Cells - metabolism; Mice; MicroRNAs - metabolism; MiR-451; mononuclear leukocytes; NF- κB; NF-kappa B - metabolism; patients; precipitin tests; Proteasome Endopeptidase Complex - metabolism; proteinases; quantitative polymerase chain reaction; reporter genes; Signal Transduction - physiology; transcription factor NF-kappa B; Transcription, Genetic - physiology; Western blotting; LMP2; TGF- β1; FN; Inflammation; ICAM-1; LMP7; TNF-α; MECL-1; IL-18; Diabetic nephropathy; NF- κB; MiR-451; MYD88