The nonsense-mediated mRNA decay pathway triggers degradation of most BRCA1 mRNAs bearing premature termination codons - Perrin-Vidoz, Laure; Sinilnikova, Olga M.; Stoppa-Lyonnet, Dominique; Lenoir, Gilbert M.; Mazoyer, Sylvie (Human molecular genetics, 2002)
Keywords: Amino Acid Substitution - genetics; Biological and medical sciences; BRCA1 Protein - genetics; Case-Control Studies; Cells, Cultured; Codon, Nonsense - genetics; Codon, Terminator; Exons - genetics; Family; Female; Female genital diseases; Gynecology. Andrology. Obstetrics; Humans; Mammary gland diseases; Medical sciences; Mutation, Missense - genetics; Open Reading Frames - genetics; Phenotype; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger - metabolism; Transcription, Genetic; Tumors; Human; Cell culture; Family study; Malignant tumor; Gene expression; Degradation; Ovary; Messenger RNA; Breast; Genetics; Mutation; Molecular biology; Lymphoblastoid cell