Interaction of cardiodigin, endogenous inhibitor of Na +,K +-ATPase, with antidigoxin and antidigitoxin antibodies

• Published in: Biochemical and biophysical research communications Vol. 129; no. 2; pp. 553 - 559
• Main Authors: Fagoo, M., Godfraind, T.
• Format: Journal Article
• Language: English
• Published: San Diego, CA Elsevier Inc 14.06.1985; Elsevier
• Subjects: Animals; Antibodies - immunology; Applied sciences; Biological Products - immunology; Biological Products - metabolism; Cardiac Glycosides; Cross Reactions; Digitoxin - immunology; Digoxin - immunology; Exact sciences and technology; Guinea Pigs; Immunochemistry; Myocardium - immunology; Myocardium - metabolism; Other techniques and industries; Sodium-Potassium-Exchanging ATPase - antagonists & inhibitors

The present study was undertaken to further characterize the immunoreactivity of cardiodigin, digitalis-like factor present in mammalian tissues. Guinea-pig heart extracts purified by reverse-phase low pressure and high pressure liquid chromatographies were analysed for their cross-reactivity with a...