High trait anxiety in healthy subjects is associated with low neuroendocrine activity during psychosocial stress

• Published in: Progress in neuro-psychopharmacology & biological psychiatry Vol. 28; no. 8; pp. 1331 - 1336
• Main Authors: Jezova, Daniela, Makatsori, Aikaterini, Duncko, Roman, Moncek, Fedor, Jakubek, Martin
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.12.2004
• Subjects: Adrenocorticotropic Hormone - blood; Adult; Analysis of Variance; Anxiety; Anxiety - blood; Anxiety - physiopathology; Epinephrine - blood; Female; Galvanic Skin Response - physiology; Heart Rate - physiology; Hormones; Humans; Hydrocortisone - blood; Male; Mental stress; Neurosecretory Systems - metabolism; Neurosecretory Systems - physiology; Norepinephrine - blood; Saliva - metabolism; Skin conductance; Stress, Psychological - blood; Stress, Psychological - physiopathology; Time Factors; STAI-T; ANOVA; ACTH; HPA; Skin conductance; Anxiety; RIA; Hormones; EDTA; IRMA; Mental stress

Altered stress responsiveness has been repeatedly related to mood and anxiety disorders. In a traditional view, a reduction of the stress response has been thought favorable. The goal of the present study was to verify the hypothesis that high anxiety is accompanied by enhanced hormone release durin...