Morphometric profile of large intestinal neuronal plexuses in normal perinatal autopsies and Hirschsprung disease

• Published in: Neurogastroenterology and motility Vol. 29; no. 3; pp. np - n/a
• Main Authors: Subramanian, H., Badhe, B. A., Toi, P. C., Sambandan, K.
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.03.2017
• Subjects: Autopsy; Cross-Sectional Studies; Enteric Nervous System - cytology; Enteric Nervous System - pathology; ganglion cells; Hirschsprung disease; Hirschsprung Disease - pathology; Humans; Infant, Newborn; Intestine, Large - cytology; Intestine, Large - innervation; Intestine, Large - pathology; morphometry; Neurons - pathology; Prospective Studies; ganglion cells; Hirschsprung disease; morphometry

Objectives To derive objective values for the diagnosis of Hirschsprung disease (HSCR) from a comparison of the morphometric profile of large intestinal neuronal plexuses in normal perinatal autopsies and surgical specimens of HSCR. Methods A cross‐sectional comparative study with 40 subjects each i...