SARS-CoV-2: Molecular Structure, Pathogenesis, Potential Therapeutic Targets, and Immune Response of the Infected Subject

• Published in: Interdisciplinary perspectives on infectious diseases Vol. 2022; pp. 1 - 10
• Main Authors: Wumba, R., Mandina, M., Nlandu, Y., Makulo, J. R., Tshimpi, A., Mbala, P., Mbangama, A., Kabututu, P., Kayembe, J. M.
• Format: Journal Article
• Language: English
• Published: Egypt Hindawi 2022; John Wiley & Sons, Inc; Wiley
• Subjects: Clinical trials; Coronaviruses; COVID-19; Enzymes; Epidemiology; Immune response; Medical research; Molecular structure; Pathophysiology; Polypeptides; Proteins; Review; RNA polymerase; Severe acute respiratory syndrome coronavirus 2; Viruses; China

Background. The pathogenic mechanisms and immune response of COVID-19 are far from clear. Through a documentary review of literature, the authors describe virological and molecular aspects of SARS-CoV-2, the intimate mechanisms of cell infection, and potential therapeutic targets. They also analyze...