Ultrafast 2‐Dimensional Image Monitoring and Array‐Based Passive Cavitation Detection for Ultrasound Contrast Agent Destruction in a Variably Sized Region

• Published in: Journal of ultrasound in medicine Vol. 33; no. 11; pp. 1957 - 1970
• Main Authors: Xu, Shanshan, Hu, Hong, Jiang, Hujie, Xu, Zhi'an, Wan, Mingxi
• Format: Journal Article
• Language: English
• Published: England American Institute of Ultrasound in Medicine 01.11.2014
• Subjects: Contrast Media - chemistry; Contrast Media - radiation effects; diagnostic ultrasound scanner; Dose-Response Relationship, Radiation; Equipment Design; Equipment Failure Analysis; Gases - chemistry; Gases - radiation effects; High-Energy Shock Waves; High-Intensity Focused Ultrasound Ablation - instrumentation; microbubble destruction; passive cavitation detection; Phantoms, Imaging; Phospholipids - chemistry; Phospholipids - radiation effects; Radiation Dosage; Reproducibility of Results; Sensitivity and Specificity; Sulfur Hexafluoride - chemistry; Sulfur Hexafluoride - radiation effects; Systems Integration; ultrafast 2-dimensional imaging; Ultrasonography, Interventional - instrumentation; variably sized focal region; variably sized focal region; diagnostic ultrasound scanner; passive cavitation detection; ultrafast 2-dimensional imaging; microbubble destruction

Objectives A combined approach was proposed, based on programmable ultrasound equipment, to simultaneously monitor surviving microbubbles and detect cavitation activity during microbubble destruction in a variably sized region for use in ultrasound contrast agent (UCA)‐enhanced therapeutic ultrasoun...