Cholesterol and triglyceride levels in first-episode psychosis: systematic review and meta-analysis

• Published in: British journal of psychiatry Vol. 211; no. 6; pp. 339 - 349
• Main Authors: Pillinger, Toby, Beck, Katherine, Stubbs, Brendon, Howes, Oliver D.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 01.12.2017; Royal College of Psychiatrists
• Subjects: Antipsychotics; Cardiovascular disease; Cholesterol; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Chronic illnesses; Citations; Density; Diabetes; Diabetes mellitus (non-insulin dependent); Early intervention; Fasting; Glucose; Health care access; High density lipoprotein; Hormones; Humans; Hypercholesterolemia; Insulin resistance; Leptin; Leptin - blood; Lipids; Lipoproteins; Low density lipoprotein; Meta-analysis; Metabolic syndrome; Mortality; Nutrition; Patients; Physical activity; Psychiatry; Psychosis; Psychotic Disorders - blood; Psychotropic drugs; Review; Review article; Schizophrenia; Systematic review; Triglycerides; Triglycerides - blood; Type 2 diabetes mellitus

The extent of metabolic and lipid changes in first-episode psychosis (FEP) is unclear. To investigate whether individuals with FEP and no or minimal antipsychotic exposure show lipid and adipocytokine abnormalities compared with healthy controls. We conducted a meta-analysis of studies examining lip...