Genetically mediated interindividual variation in analgesic responses to cyclooxygenase inhibitory drugs - Lee, Yun-Sil; Kim, Hyungsuk; Wu, Tian-Xia; Wang, Xiao-Min; Dionne, Raymond A (Clinical pharmacology and therapeutics, 2006)
Keywords: Adolescent; Adult; Aged; Cyclooxygenase 1 - biosynthesis; Cyclooxygenase 1 - genetics; Cyclooxygenase 2 - biosynthesis; Cyclooxygenase 2 - genetics; Cyclooxygenase Inhibitors - therapeutic use; Female; Haplotypes; Humans; Ibuprofen - therapeutic use; Lactones - therapeutic use; Male; Membrane Proteins - biosynthesis; Membrane Proteins - genetics; Middle Aged; Pain, Postoperative - drug therapy; Pain, Postoperative - genetics; Pharmacogenetics; Polymorphism, Single Nucleotide; Sulfones - therapeutic use