Kaempferol suppresses cell migration through the activation of the ERK signaling pathways in ARPE‐19 cells - Chien, Hsiang‐Wen; Wang, Kai; Chang, Yuan‐Yen; Hsieh, Yi‐Hsien; Yu, Nuo‐Yi; Yang, Shun‐Fa; Lin, Hui‐Wen (Environmental toxicology, 2019)
Keywords: Adult; Anticancer properties; Cancer; Cell activation; Cell adhesion & migration; Cell Line; Cell lines; Cell migration; cell movement; Cell Movement - drug effects; Cells; Enzymatic activity; Enzyme activity; epithelial cells; Epithelial Cells - cytology; Epithelial Cells - drug effects; Epithelial Cells - metabolism; epithelium; ERK1/2 signaling; Extracellular; Extracellular signal-regulated kinase; gelatinase A; Humans; Kaempferol; Kaempferols - pharmacology; Kinases; Male; MAP Kinase Signaling System - drug effects; Matrix metalloproteinase; Matrix Metalloproteinase 2 - genetics; Matrix Metalloproteinase 2 - metabolism; Matrix Metalloproteinase 9 - genetics; Matrix Metalloproteinase 9 - metabolism; Metalloproteinase; Metastases; migration; mitogen-activated protein kinase; Mitogen-Activated Protein Kinase 1 - genetics; Mitogen-Activated Protein Kinase 1 - metabolism; Mitogen-Activated Protein Kinase 3 - genetics; Mitogen-Activated Protein Kinase 3 - metabolism; MMP‐2; neoplasm cells; Phosphorylation - drug effects; protein synthesis; Proteins; Retina; Retinal pigment epithelium; Retinal Pigment Epithelium - drug effects; Retinal Pigment Epithelium - metabolism; Signal transduction; Signaling; Tumor cell lines; Young Adult; migration; MMP-2; kaempferol; ERK1/2 signaling