Approximate Weight of 1:1000 Topical Epinephrine on Wrung-Out Epinephrine-Soaked Pledgets

• Published in: Otolaryngology-head and neck surgery Vol. 162; no. 1; p. 60
• Main Authors: Kuhar, Hannah N, Han, Xiaoxia, Penning, Donald H, Craig, John R
• Format: Journal Article
• Language: English
• Published: England 01.01.2020
• Subjects: Administration, Intranasal; Administration, Topical; Adult; Blood Loss, Surgical - prevention & control; Cohort Studies; Dose-Response Relationship, Drug; Endoscopy - methods; Epinephrine - administration & dosage; Female; Hemostatic Techniques; Humans; Male; Middle Aged; Nasal Cavity - drug effects; Nasal Cavity - surgery; Paranasal Sinus Diseases - diagnosis; Paranasal Sinus Diseases - surgery; Paranasal Sinuses - surgery; Prognosis; Prospective Studies; Tertiary Care Centers; Treatment Outcome; United States; Vasoconstrictor Agents - administration & dosage; United States; topical epinephrine; endoscopic sinus surgery; hemostasis

Topical 1:1000 epinephrine solution is commonly applied intranasally with cottonoid pledgets in endoscopic sinonasal surgery for local vasoconstriction and hemostasis. Pledgets are typically submerged in epinephrine solution and applied without measurement. Hemodynamic complications have been report...