Hexamethonium reverses the lethal cardiopulmonary damages in a rat model of brainstem lesions mimicking fatal enterovirus 71 encephalitis - Lu, Wen-Hsien; Hsieh, Kai-Sheng; Lu, Pei-Jung; Wu, Yi-Shan; Ho, Wen-Yu; Lai, Chi-Cheng; Wang, Jyh-Seng; Ger, Luo-Ping; Hsiao, Michael; Tseng, Ching-Jiunn (Critical care medicine, 2013)
Keywords: Animals; Biopsy, Needle; Brain Stem - drug effects; Brain Stem - pathology; Catecholamines - metabolism; Diagnosis, Differential; Disease Models, Animal; Encephalitis, Viral - complications; Encephalitis, Viral - drug therapy; Encephalitis, Viral - mortality; Encephalitis, Viral - pathology; Enterovirus A, Human - pathogenicity; Enterovirus Infections - complications; Enterovirus Infections - drug therapy; Enterovirus Infections - mortality; Enterovirus Infections - pathology; Ganglionic Blockers - administration & dosage; Hexamethonium - administration & dosage; Hypertension - etiology; Hypertension - pathology; Hypertension - prevention & control; Immunohistochemistry; Male; Pulmonary Edema - etiology; Pulmonary Edema - pathology; Pulmonary Edema - prevention & control; Random Allocation; Rats; Rats, Sprague-Dawley; Survival Rate