From Proteomics to the Analysis of Single Protein Molecules

• Published in: International journal of molecular sciences Vol. 25; no. 19; p. 10308
• Main Authors: Ponomarenko, Elena A, Ivanov, Yuri D, Valueva, Anastasia A, Pleshakova, Tatyana O, Zgoda, Victor G, Vavilov, Nikita E, Ilgisonis, Ekaterina V, Lisitsa, Andrey V, Archakov, Alexander I
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.10.2024; MDPI
• Subjects: atomic force microscopy; Biomarkers; Biopsy; Diagnostic equipment (Medical); Humans; Limit of Detection; Mass Spectrometry - methods; Methods; molecular counters; Opinion; protein detection; Proteins; Proteins - analysis; proteomics; Proteomics - methods; sensitivity in bioanalysis; Sensors; single biomacromolecule; Israel; molecular counters; proteomics; mass spectrometry; protein detection; sensitivity in bioanalysis; single biomacromolecule; atomic force microscopy; limit of detection

Limit of detection (LoD) is a term that is used to characterize the sensitivity of an analytical method. The existing limitation of the sensitivity of analysis using modern mass spectrometry methods has been experimentally shown to be a limiting factor in the application of proteomic technologies in...