Clinical and Histological Aspects of Toenail Onychomycosis Caused by Aspergillus spp.: 34 Cases Treated with Weekly Intermittent Terbinafine

• Published in: Dermatology (Basel) Vol. 209; no. 2; pp. 104 - 110
• Main Authors: Gianni, Claudia, Romano, Clara
• Format: Journal Article
• Language: English
• Published: Basel, Switzerland Karger 01.01.2004; S. Karger AG
• Subjects: Administration, Oral; Aspergillosis - diagnosis; Aspergillosis - drug therapy; Aspergillus - classification; Biological and medical sciences; Biopsy, Needle; Clinical and Laboratory Investigations; Cohort Studies; Dermatology; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fingers & toes; Follow-Up Studies; Fungi; Human mycoses; Humans; Immunohistochemistry; Infections; Infectious diseases; Italy; Male; Medical sciences; Medical treatment; Mycoses; Mycoses of the skin; Naphthalenes - therapeutic use; Onychomycosis - diagnosis; Onychomycosis - drug therapy; Risk Assessment; Severity of Illness Index; Treatment Outcome; Italy; Non-dermatophytic onychomycosis; Aspergillus spp; Terbinafine pulse therapy; Human; Skin disease; Mycosis; Dermatology; Clinical form; Histology; Toe; Allylic compound; Onychomycosis; Terbinafine; Fungi; Infection; Aspergillus; Symptomatology; Antifungal agent; Chemotherapy; Amine; Treatment; Nail disease; Fungi Imperfecti; Thallophyta

Background: Non-dermatophytic onychomycoses represent 1.45–17.6% of all fungal nail infections. Epidemiological studies have shown that Aspergillus spp. are emerging fungal agents of toenail onychomycosis. Indeed, after Scopulariopsis spp. the genus Aspergillus is the second most common agent of non...