Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel disease

• Published in: Human molecular genetics Vol. 9; no. 9; pp. 1425 - 1432
• Main Authors: Cho, J H, Nicolae, D L, Ramos, R, Fields, C T, Rabenau, K, Corradino, S, Brant, S R, Espinosa, R, LeBeau, M, Hanauer, S B, Bodzin, J, Bonen, D K
• Format: Journal Article
• Language: English
• Published: England Oxford Publishing Limited (England) 22.05.2000
• Subjects: chromosome 1; Chromosomes, Human, Pair 1; Ethnic Groups; Family Health; Female; Genetic Linkage; Genetic Markers; Genetic Predisposition to Disease; Haplotypes; Humans; In Situ Hybridization, Fluorescence; inflammatory bowel disease; Inflammatory Bowel Diseases - genetics; Linkage Disequilibrium; Lod Score; Male; Middle East - ethnology; Phenotype; Physical Chromosome Mapping; Polymorphism, Single Nucleotide; United States - epidemiology; Middle East; United States

The idiopathic inflammatory bowel diseases (IBDs), consisting of Crohn's disease and ulcerative colitis, are complex genetic disorders involving chronic inflammation of the intestines. Multiple genetic loci have been implicated through genome-wide searches, but refinement of localization suffic...