Combination approach using neoadjuvant therapy with radical prostatectomy for improving oncological outcomes of high-risk prostate cancer: a narrative review

• Published in: Translational cancer research Vol. 13; no. 7; pp. 3889 - 3897
• Main Authors: Nakane, Keita, Kawase, Makoto, Kato, Daiki, Iinuma, Koji, Kawase, Kota, Takeuchi, Shinichi, Tobisawa, Yuki, Ito, Takayasu, Koie, Takuya
• Format: Journal Article
• Language: English
• Published: China AME Publishing Company 31.07.2024
• Subjects: Review; Prostate cancer (PCa); neoadjuvant therapy; treatment outcome; radiotherapy (RT); surgery

Prostate cancer (PCa) is the most common cancer in men. High-risk PCa is associated with an increased risk of PCa-related death. The combined use of androgen deprivation therapy (ADT) is essential to improve oncological outcomes in patients with high-risk PCa, and relatively long-term ADT administra...