Naringenin suppresses epithelial ovarian cancer by inhibiting proliferation and modulating gut microbiota

• Published in: Phytomedicine (Stuttgart) Vol. 106; p. 154401
• Main Authors: Lin, Caiji, Zeng, Zheng, Lin, Yiru, Wang, Pengfei, Cao, Danli, Xie, Kaihong, Luo, Yao, Yang, Hao, Yang, Jiaming, Wang, Wenxue, Luo, LingJie, Lin, Huihui, Chen, Hang, Zhao, Yufan, Shi, Yongwei, Gao, Zixiang, Liu, Huidi, Liu, Shu-Lin
• Format: Journal Article
• Language: English
• Published: Elsevier GmbH 01.11.2022
• Subjects: Gut microbiota; Naringenin; Ovarian cancer; PI3K; Gut microbiota; PCoA; Naringenin; IHC; p.o., per os; i.p; NMDS; PFA; EGFR; Ovarian cancer; PCA; MMP; PI3K; CCND1; CMC-Na; EOC; HE; HPLC

Ovarian cancer has the highest mortality among all gynecological malignancies; currently, no effective therapeutics are available for its treatment. Naringenin has been shown to inhibit the progression of various cancers, but its inhibitory effect on ovarian cancer remains unknown. This study aimed...