A 28-week, randomized, double-blind study of olanzapine versus aripiprazole in the treatment of schizophrenia

• Published in: The journal of clinical psychiatry Vol. 70; no. 4; p. 572
• Main Authors: Kane, John M, Osuntokun, Olawale, Kryzhanovskaya, Ludmila A, Xu, Wen, Stauffer, Virginia L, Watson, Susan B, Breier, Alan
• Format: Journal Article
• Language: English
• Published: United States 01.04.2009
• Subjects: Adult; Affect; Antipsychotic Agents - therapeutic use; Aripiprazole; Benzodiazepines - therapeutic use; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Female; Humans; Male; Olanzapine; Piperazines - therapeutic use; Quinolones - therapeutic use; Schizophrenia - drug therapy; Severity of Illness Index; Surveys and Questionnaires

To evaluate the effectiveness of olanzapine versus aripiprazole in patients with schizophrenia. Patients aged 18 to 65 years with schizophrenia (diagnosed according to DSM-IV-TR criteria) were randomly assigned to either olanzapine (n = 281) or aripiprazole (n = 285) for 28 weeks of double-blind tre...