Targeting Cognitive Frailty: Clinical and Neurobiological Roadmap for a Single Complex Phenotype

• Published in: Journal of Alzheimer's disease Vol. 47; no. 4; p. 793
• Main Authors: Panza, Francesco, Seripa, Davide, Solfrizzi, Vincenzo, Tortelli, Rosanna, Greco, Antonio, Pilotto, Alberto, Logroscino, Giancarlo
• Format: Journal Article
• Language: English
• Published: Netherlands 11.08.2015
• Subjects: Aged; Aged, 80 and over; Aging - physiology; Aging - psychology; Cognition - physiology; Cognition Disorders - physiopathology; Frail Elderly - psychology; Humans; physical frailty; subjective cognitive decline; Alzheimer’s disease; vascular dementia; dementia; frailty index; mild cognitive impairment; cognitive frailty; cognitive disorders

Late-life cognitive disorders may be prevented by influencing age-related conditions such as frailty, characterized by decreased resistance to stressors and increased risk for adverse health outcomes. In the present review article, we examined clinical and epidemiological studies investigating the p...