Synergie between molecular imprinted polymer based on solid-phase extraction and quartz crystal microbalance technique for 8-OHdG sensing

• Published in: Biosensors & bioelectronics Vol. 24; no. 4; pp. 742 - 747
• Main Authors: Ersöz, Arzu, Diltemiz, S. Emir, Özcan, A. Atılır, Denizli, Adil, Say, Rıdvan
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 01.12.2008
• Subjects: 8-Hydroxy-2′-deoxyguanosine (8-OHdG); Biosensing Techniques - instrumentation; Biosensing Techniques - methods; Chelating Agents - chemistry; Crystallization - methods; Deoxyguanosine - analogs & derivatives; Deoxyguanosine - analysis; Equipment Design; Equipment Failure Analysis; Metal–chelate interaction; Micro-Electrical-Mechanical Systems - instrumentation; Molecularly imprinted polymer (MIP); Polymers - chemistry; Quartz crystal microbalance (QCM); Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction - instrumentation; Solid Phase Extraction - methods; Surface Properties; Quartz crystal microbalance (QCM); 8-Hydroxy-2′-deoxyguanosine (8-OHdG); Molecularly imprinted polymer (MIP); Metal–chelate interaction

Recently, the 8-hydroxy-2′-deoxyguanosine (8-OHdG) has been used as a marker to determine the oxidative stress. There is no any cheap and easy determination method based on chips and sensor systems for the determination of 8-OHdG. In this study, we have proposed imprinting methods for 8-OHdG recogni...