Diagnostic relevance of ADAMTS13 activity: evaluation of 28 patients with thrombotic thrombocytopenic purpura - hemolytic uremic syndrome clinical diagnosis

• Published in: Srpski arhiv za celokupno lekarstvo Vol. 141; no. 7-8; pp. 466 - 474
• Main Authors: Vucelić, Dragica, Miković, Danijela, Rajić, Zoran, Savić, Nebojsa, Budisin, Zivko, Antonijević, Nebojsa M, Obradović, Slobodan, Jevtić, Dragana, Palla, Roberta, Valsecchio, Carla, Peyvandi, Flora
• Format: Journal Article
• Language: English
• Published: Serbia Serbian Medical Society 2013
• Subjects: ADAM Proteins - metabolism; ADAMTS13; ADAMTS13 Protein; diagnosis; hemolytic uremic syndrome; Hemolytic-Uremic Syndrome - enzymology; Hemolytic-Uremic Syndrome - epidemiology; Hemolytic-Uremic Syndrome - metabolism; Humans; Purpura, Thrombotic Thrombocytopenic - enzymology; Purpura, Thrombotic Thrombocytopenic - epidemiology; Purpura, Thrombotic Thrombocytopenic - metabolism; Serbia - epidemiology; thrombotic thrombocytopenic purpura

The significance of ADAMTS13 (a disintegrin and metalloproteinase with thrombospondin motif-13) activity for diagnosis and therapy of thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS) is still a controversial issue. The aim of this report was to analyze the value of ADAMT...