Prognosis of Patients with Cirrhosis and AKI Who Initiate RRT

• Published in: Clinical journal of the American Society of Nephrology Vol. 13; no. 1; pp. 16 - 25
• Main Authors: Allegretti, Andrew S., Parada, Xavier Vela, Eneanya, Nwamaka D., Gilligan, Hannah, Xu, Dihua, Zhao, Sophia, Dienstag, Jules L., Chung, Raymond T., Thadhani, Ravi I.
• Format: Journal Article
• Language: English
• Published: United States American Society of Nephrology 06.01.2018
• Subjects: Acute Kidney Injury - diagnosis; Acute Kidney Injury - mortality; Acute Kidney Injury - therapy; Comorbidity; Female; Health Status; Hepatorenal Syndrome - diagnosis; Hepatorenal Syndrome - mortality; Hepatorenal Syndrome - therapy; Humans; Liver Cirrhosis - diagnosis; Liver Cirrhosis - mortality; Liver Cirrhosis - therapy; Liver Transplantation - adverse effects; Liver Transplantation - mortality; Male; Massachusetts - epidemiology; Middle Aged; Original; Renal Dialysis - adverse effects; Renal Dialysis - mortality; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome; Waiting Lists; Massachusetts; dialysis; renal replacement therapy; Prognosis; continuous renal replacement therapy; Humans; Proportional Hazards Models; acute tubular necrosis; Liver Cirrhosis; Survival Analysis; hepatorenal syndrome; hemodialysis; Retrospective Studies; acute kidney injury; futility; Kidney Tubular Necrosis, Acute; cirrhosis; liver transplantation; renal dialysis; transplant-free survival

Literature on the prognosis of patients with cirrhosis who require RRT for AKI is sparse and is confounded by liver transplant eligibility. An update on outcomes in the nonlisted subgroup is needed. Our objective was to compare outcomes in this group between those diagnosed with hepatorenal syndrome...