REporting recommendations for tumour MARKer prognostic studies (REMARK)

• Published in: European journal of cancer (1990) Vol. 41; no. 12; pp. 1690 - 1696
• Main Authors: McShane, Lisa M., Altman, Douglas G., Sauerbrei, Willi, Taube, Sheila E., Gion, Massimo, Clark, Gary M.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.08.2005; Elsevier
• Subjects: Biological and medical sciences; Biomarkers, Tumor - analysis; Biomedical Research - standards; EORTC; Guidelines; Humans; Information Dissemination; Medical sciences; NCI; Neoplasms - diagnosis; Pharmacology. Drug treatments; Prognostic; REMARK; Research Design - statistics & numerical data; Tumors; Tumour markers; Tumour markers; NCI; REMARK; EORTC; Prognostic; Guidelines; Cancerology; Prognosis; Tumoral marker; Pharmacology; Recommendation; European Organization for Research and Treatment of Cancer

Despite years of research and hundreds of reports on tumour markers in oncology, the number of markers that have emerged as clinically useful is pitifully small. Often initially reported studies of a marker show great promise, but subsequent studies on the same or related markers yield inconsistent...