Drug-eluting Microneedles Embedded with Nanoparticles for Anti-inflammatory Purposes

Microneedle (MN) technology is used to deliver drugs transdermally in a minimally invasive manner with self-administered properties to enable controlled drug release. MNs can improve drug permeation efficiency into the skin by creating tiny holes through which the drugs can directly pass through the...

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Published inBiotechnology and bioprocess engineering Vol. 28; no. 4; pp. 507 - 518
Main Authors Kim, Dongmin, Baek, Seungho, Go, Anna, Park, Heekyung, Ma, Rongen, Lee, Donghyun
Format Journal Article
LanguageEnglish
Published Seoul The Korean Society for Biotechnology and Bioengineering 01.08.2023
Springer Nature B.V
한국생물공학회
Subjects
Anti-inflammatory agents
Barrier layers
biodegradability
Biodegradation
Biotechnology
Chemistry
Chemistry and Materials Science
digestive tract
Dissolution
Drug delivery
Drug delivery systems
Drugs
Gastrointestinal diseases
Gastrointestinal system
Gastrointestinal tract
Industrial and Production Engineering
Inflammation
Irritation
mucosa
Nanoparticles
Needles
permeability
Polymers
Production methods
Review Paper
Side effects
Skin
skin irritation
Stratum corneum
생물공학
microneedle
dissolving microneedle
anti-inflammatory
nanoparticle
biodegradable polymer
transdermal drug delivery
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Abstract Microneedle (MN) technology is used to deliver drugs transdermally in a minimally invasive manner with self-administered properties to enable controlled drug release. MNs can improve drug permeation efficiency into the skin by creating tiny holes through which the drugs can directly pass through the stratum corneum, which is the largest barrier layer of the skin. MNs can be used to deliver drugs transdermally by avoiding the gastrointestinal tract route when administering anti-inflammatory drugs so as to avoid damage to the mucous membrane, which can cause gastrointestinal disorders. Dissolving microneedles (DMNs) in biodegradable polymers allows quick dissolution after skin penetration; this can prevent side effects, such as skin irritation due to leftover MN debris on the skin. However, the drugs may be nonspecifically delivered after being released from the MNs, which may reduce their efficacy. Nanoparticles are widely used as drug-delivery systems because they prevent unintentional drug leakage and can specifically deliver drugs through modifications on the nanoparticle surfaces. When such nanoparticles are applied to MNs, the drug release can be controlled and local administration through the skin is possible, making drug delivery more effective. In this review, we describe the materials and manufacturing methods of DMNs as well as recent trends in drug-delivery research using nanoparticle-embedded DMNs to control release of anti-inflammatory drugs.
AbstractList Microneedle (MN) technology is used to deliver drugs transdermally in a minimally invasive manner with self-administered properties to enable controlled drug release. MNs can improve drug permeation efficiency into the skin by creating tiny holes through which the drugs can directly pass through the stratum corneum, which is the largest barrier layer of the skin. MNs can be used to deliver drugs transdermally by avoiding the gastrointestinal tract route when administering anti-inflammatory drugs so as to avoid damage to the mucous membrane, which can cause gastrointestinal disorders. Dissolving microneedles (DMNs) in biodegradable polymers allows quick dissolution after skin penetration; this can prevent side effects, such as skin irritation due to leftover MN debris on the skin. However, the drugs may be nonspecifically delivered after being released from the MNs, which may reduce their efficacy. Nanoparticles are widely used as drug-delivery systems because they prevent unintentional drug leakage and can specifically deliver drugs through modifications on the nanoparticle surfaces. When such nanoparticles are applied to MNs, the drug release can be controlled and local administration through the skin is possible, making drug delivery more effective. In this review, we describe the materials and manufacturing methods of DMNs as well as recent trends in drug-delivery research using nanoparticle-embedded DMNs to control release of anti-inflammatory drugs.
Microneedle (MN) technology is used to deliver drugs transdermally in a minimally invasive manner with self-administered properties to enable controlled drug release. MNs can improve drug permeation efficiency into the skin by creating tiny holes through which the drugs can directly pass through the stratum corneum, which is the largest barrier layer of the skin. MNs can be used to deliver drugs transdermally by avoiding the gastrointestinal tract route when administering anti-inflammatory drugs so as to avoid damage to the mucous membrane, which can cause gastrointestinal disorders. Dissolving microneedles (DMNs) in biodegradable polymers allows quick dissolution after skin penetration; this can prevent side effects, such as skin irritation due to leftover MN debris on the skin. However, the drugs may be nonspecifically delivered after being released from the MNs, which may reduce their efficacy. Nanoparticles are widely used as drug-delivery systems because they prevent unintentional drug leakage and can specifically deliver drugs through modifications on the nanoparticle surfaces. When such nanoparticles are applied to MNs, the drug release can be controlled and local administration through the skin is possible, making drug delivery more effective. In this review, we describe the materials and manufacturing methods of DMNs as well as recent trends in drug-delivery research using nanoparticleembedded DMNs to control release of anti-inflammatory drugs. KCI Citation Count: 0
Author Go, Anna
Park, Heekyung
Ma, Rongen
Baek, Seungho
Kim, Dongmin
Lee, Donghyun
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  givenname: Dongmin
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  givenname: Anna
  surname: Go
  fullname: Go, Anna
  organization: Department of Biomedical Engineering, School of Integrative Engineering, Chung-Ang University
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  givenname: Heekyung
  surname: Park
  fullname: Park, Heekyung
  organization: Department of Biomedical Engineering, School of Integrative Engineering, Chung-Ang University
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  givenname: Rongen
  surname: Ma
  fullname: Ma, Rongen
  organization: Department of Biomedical Engineering, School of Integrative Engineering, Chung-Ang University
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  surname: Lee
  fullname: Lee, Donghyun
  email: dhlee@cau.ac.kr
  organization: Department of Biomedical Engineering, School of Integrative Engineering, Chung-Ang University
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Cites_doi 10.1002/adhm.201300312
10.1208/s12249-019-1611-9
10.1016/j.jddst.2021.102711
10.1039/D1NR07708B
10.1002/smll.202104657
10.1016/j.ejpb.2020.06.025
10.1016/j.carbpol.2017.10.044
10.1016/j.jddst.2020.102284
10.1016/j.cej.2021.134196
10.1016/j.jconrel.2020.12.025
10.1021/acsami.7b18293
10.1016/j.ijbiomac.2022.07.021
10.1007/s10311-020-01061-2
10.1016/j.mtbio.2022.100223
10.1002/adem.202001355
10.1021/acsami.9b15668
10.1002/adfm.202004407
10.3390/ma11091625
10.1016/j.ejps.2021.106075
10.1016/j.biopha.2018.10.078
10.2147/IJN.S33607
10.1016/j.biomaterials.2012.12.041
10.1016/j.ijpharm.2021.120301
10.3390/polym13183043
10.1016/j.jconrel.2020.09.008
10.1002/smll.201001091
10.1016/j.ijpharm.2019.118741
10.1016/j.msec.2020.111544
10.1007/s13346-017-0470-8
10.1002/adma.200902418
10.1002/jps.20745
10.3389/fbioe.2019.00489
10.1016/j.ejps.2017.12.025
10.1016/j.jconrel.2020.06.039
10.1016/j.biomaterials.2011.01.014
10.3390/polym12061392
10.3390/mi12111321
10.3390/pharmaceutics9030027
10.1080/10717544.2022.2120927
10.1016/j.lfs.2021.119877
10.1007/s11814-016-0240-1
10.1016/j.actbio.2017.11.004
10.1016/j.biopha.2022.113492
10.1016/j.matdes.2022.111363
10.1016/j.jddst.2018.04.009
10.1016/j.ejpb.2020.07.005
10.3389/fphar.2020.00524
10.1111/jocd.12426
10.1016/j.bioactmat.2022.12.007
10.1016/j.jddst.2019.101464
10.1016/j.cej.2021.130561
10.1007/s12257-015-0634-7
10.1038/s41598-018-19789-x
10.1038/s41598-022-05912-6
10.1016/j.ijpharm.2016.10.054
10.3390/pharmaceutics13030357
10.3390/pharmaceutics11050209
10.1016/j.ijpharm.2021.120749
10.1016/j.jddst.2021.102537
10.1007/s12247-021-09586-x
10.1021/acsomega.2c01993
10.1016/j.jtice.2015.01.003
10.1016/j.actbio.2019.07.048
10.1002/adfm.202104092
10.1002/adma.200701205
10.3390/nano10101970
10.3390/pharmaceutics10040191
10.1016/j.jddst.2019.101487
10.1016/j.biopha.2017.07.019
10.1039/C9TB02061F
10.1016/j.ijpharm.2021.121211
10.1002/adhm.201900898
10.1007/s10934-022-01371-6
10.1007/s13346-021-01006-4
10.1007/s13346-021-00977-8
10.3390/mi9010040
10.1111/ics.12617
10.1002/adhm.202100056
10.1021/acsbiomaterials.0c00120
10.1016/j.biomaterials.2012.06.065
10.1016/j.ijbiomac.2022.06.131
10.1016/j.jddst.2020.102192
10.1016/j.pnsc.2020.09.016
10.1016/j.msec.2020.111793
10.1002/admt.201900552
10.1002/adhm.201900896
10.1016/j.jconrel.2022.09.025
10.1016/j.msec.2019.110248
10.1002/adhm.202100996
10.1016/j.ejpb.2013.10.001
10.1016/j.ejpb.2018.02.009
10.1166/mex.2021.1893
10.1016/j.ijbiomac.2021.06.059
10.2147/IJN.S371183
10.1007/s12247-022-09670-w
10.1088/1361-6439/ac0513
10.1111/1346-8138.16732
10.1016/j.jconrel.2013.05.026
10.1007/s40005-021-00512-4
10.1016/j.biomaterials.2021.121142
10.1016/j.ejpb.2021.06.005
10.3390/nano10040787
10.3390/pharmaceutics12111101
10.1016/j.jddst.2020.101818
10.1007/s11095-017-2223-2
10.1016/j.matdes.2021.109485
10.3390/pharmaceutics14020409
10.1016/j.jconrel.2021.08.054
10.1016/j.actbio.2022.06.046
10.1021/bm301293d
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dissolving microneedle
anti-inflammatory
nanoparticle
biodegradable polymer
transdermal drug delivery
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PublicationYear 2023
Publisher The Korean Society for Biotechnology and Bioengineering
Springer Nature B.V
한국생물공학회
Publisher_xml – name: The Korean Society for Biotechnology and Bioengineering
– name: Springer Nature B.V
– name: 한국생물공학회
References Liang, Chen, Zhang, Zhang, Liu, Shen, Cui, Guo (CR32) 2020; 55
Mishra, Bansal, Verma, Yadav, Thakur, Sudhakar, Rosenholm (CR35) 2018; 10
Yang, Jeong, Lim, Park (CR45) 2021; 201
Chang, Zheng, Chew, Xu (CR85) 2020; 5
Lee, Jung (CR80) 2012; 33
Deng, Zhang, Shen, He, Wu, Liao, Yuan (CR86) 2020; 7
Dalvi, Kharat, Thakor, Bhavana, Singh, Mehra (CR27) 2021; 284
Zhao, Zhang, Abu-Ershaid, Li, Li, Naser, Dai, Abbate, Donnelly (CR20) 2021; 10
Meng, Zhang, Li (CR14) 2020; 30
Fang, Liu, Hsu, Chen, Chiang, Wang, Hu (CR73) 2020; 12
Uddin, Scoutaris, Economidou, Giraud, Chowdhry, Donnelly, Douroumis (CR77) 2020; 107
Du, Liu, Zhu, Lan, Li, Zhang, Zhu, Tao (CR54) 2019; 11
Raza, Hayat, Bilal, Iqbal, Wang (CR8) 2020; 58
Lee, Lee, Jung (CR41) 2011; 32
Permana, Paredes, Volpe-Zanutto, Anjani, Utomo, Donnelly (CR108) 2020; 154
De Decker, Logé, Hoeksema, Speeckaert, Blondeel, Monstrey, Claes (CR42) 2023; 50
Lee, Choi, Felner, Prausnitz (CR64) 2011; 7
Prabahar, Udhumansha, Elsherbiny, Qushawy (CR112) 2022; 29
Shi, Zhou, Wang, Zhu, Lin, Lei, Vakal, Wang, Li (CR46) 2022; 18
Abuçafy, Caetano, Chiari-Andréo, Fonseca-Santos, do Santos, Chorilli, Chiavacci (CR93) 2018; 127
Kim, Kim, Yang, Lee, Jung (CR81) 2013; 170
Gorantla, Dabholkar, Sharma, Rapalli, Alexander, Singhvi (CR31) 2021; 184
Huang, Li, Li, Wang, Wang, Li (CR79) 2021; 31
Chen, Gad, Chobisa, Li, Yeo (CR1) 2021; 330
Resnik, Možek, Pečar, Janež, Urbančič, Iliescu, Vrtačnik (CR34) 2018; 9
Ahmad, Khan, Siddique, Sarwar, Shahnaz, Hussain, Bukhari, Hussain, Sohail (CR69) 2020; 21
Yang, Jia, Li, Ma, Lv, Jia, He, Zeng, Luo, Yu (CR105) 2022; 215
Khosraviboroujeni, Mirdamadian, Minaiyan, Taheri (CR47) 2022; 12
Li, He, Deng, Zhang, Lin (CR70) 2020; 8
Bhatnagar, Saju, Cheerla, Gade, Garg, Venuganti (CR74) 2018; 8
Tariq, Ashraf, Tayyaba (CR26) 2021; 17
Yang, Zhang, Hu, Xu, Jiang, Shrike Zhang, Xie (CR84) 2021; 426
Lei, Li, Wang, Cui, Qiu, Zhou, Jiang, Li, Zhao, Ni, Wang, Xia (CR106) 2022; 217
Avcil, Çelik (CR29) 2021; 12
Hou, Quan, Yang, Lu, Chen, Yang, Wang, Liu, Pan, Wu (CR2) 2019; 8
Jung, Jin (CR17) 2021; 51
Nguyen, Do, Lac, Nguyen, Le (CR11) 2022; 30
Jung, Kim, Lee, Choi, Kim (CR15) 2020; 30
Pontes-Quero, Benito-Garzón, Pérez Cano, Aguilar, Vázquez-Lasa (CR88) 2021; 121
Yan, Weng, Shen, Wang, Fang, Zheng, Yang, Yang (CR49) 2021; 13
Waghule, Singhvi, Dubey, Pandey, Gupta, Singh, Dua (CR38) 2019; 109
Dou, Li, Li, Guo, Zhang (CR3) 2020; 327
Elahpour, Pahlevanzadeh, Kharaziha, Bakhsheshi-Rad, Ramakrishna, Berto (CR30) 2021; 597
Fam, Chee, Yong, Ho, Mariatulqabtiah, Tan (CR87) 2020; 10
Permana, Mir, Utomo, Donnelly (CR109) 2020; X2
Dong, Li, Li, Xu, Liu, Du, Zhang, Huang, Zhu, Ren, Xie, Wang, Zhou, Shen, Zhu, Tao (CR52) 2018; 10
Hong, Ko, Choi, Li, Kim, Park, Kim (CR43) 2018; 17
Hua (CR7) 2020; 11
Song, Wang, Chen, Jin, Wang, Lu, Wang (CR21) 2021; 63
Altameemi, Abd-Alhammid (CR97) 2022; 13
Sullivan, Murthy, Prausnitz (CR71) 2008; 20
Ye, Yang, Li, Zheng, Yang, Li, Liu, Jiang (CR33) 2020; 6
Huang, Gou, Yue, Zhao, Zeng, Qu, Zhang (CR102) 2022; 224
CR61
Zhang, Guo, Wang, Yang, Ling, Zhang (CR75) 2021; 604
Park, Ha, Choi, Kim, Park, Choi, Kim, Sung (CR59) 2016; 21
Long, Liu, Li, Hu, He, Lu, Wang, Yang, Wang (CR100) 2022; 14
Chen, Han, Liao, Hu, Hu, Gao, Qiu (CR40) 2020; 55
Phatale, Vaiphei, Jha, Patil, Agrawal, Alexander (CR13) 2022; 351
Chaudhary, Aqil, Sultana, Kalam (CR9) 2019; 51
Lee, Lee, Lee, Jung (CR78) 2010; 22
Meena, Gupta, Ahuja, Singh, Bhaskar, Panda (CR92) 2020; 18
Yan, Raphael, Zhu, Wang, Chen, Tang, Deng, Sant, Zhu, Choy, Gale, Prow, Chen (CR62) 2014; 3
Chi, Huang, Kang, Dai, Liu, Xu, Zhong (CR58) 2022; 168
Ita (CR76) 2017; 93
Oh, Hwang, Na (CR72) 2022; 7
Khan, Razzaq, Khan, Rehman, Khan, Khan, Khan, Althobaiti, Menaa, Iqbal, Khan (CR89) 2022; 14
Sadeqi, Kiaee, Zeng, Nejad, Sonkusale (CR28) 2022; 12
Yerneni, Yalcintas, Smith, Averick, Campbell, Ozdoganlar (CR101) 2022; 149
Chandrasekharan, Hwang, Seong, Park, Kim, Yang (CR48) 2019; 11
Feng, Song, Zhai (CR90) 2012; 7
Wu, Shrestha, Iapichino, Cai, Kim, Stoeber (CR37) 2021; 61
Chen, Ling, Lai, Pramudityo (CR68) 2012; 13
Chen, Lai, Chiu, Wu, Shiau, Chen (CR66) 2019; 97
Yiyun, Man, Xu, Fu, Wang, Wang, Wen (CR10) 2007; 96
Chen, Shyu, Chen (CR44) 2018; 11
Shah, Eldridge, Palombo, Harding (CR91) 2016; 515
Guo, Cheng, Zhao, Hou, Zhang, Feng (CR98) 2019; 572
Jang, Baek, Kang, Yang, Kim, Jung (CR55) 2020; 42
Zhang, Hu, Cai, Wu, Li, Dong (CR4) 2022; 14
Chen, Huang, Lai, Ling (CR67) 2013; 34
Seetharam, Choudhry, Bakhrebah, Abdulaal, Gupta, Rizvi, Alam, Siddaramaiah, Gowda, Moin (CR6) 2020; 12
Ko, Lee, Chen, Tsai (CR24) 2015; 51
Yao, Chi, Wang, Zhao, Luo, Wang (CR107) 2021; 10
Howells, Blayney, Gualeni, Birchall, Eng, Ashraf, Sharma, Guy (CR22) 2022; 171
Aung, Ngawhirunpat, Rojanarata, Patrojanasophon, Opanasopit, Pamornpathomkul (CR51) 2021; 61
Hadisoewignyo, Hartono, Kresnamurti, Soeliono, Nataline, Prakoso, Aulia (CR5) 2018; 9
Jacob, Nair, Shah, Sreeharsha, Gupta, Shinu (CR16) 2021; 13
Zhang, Li, Chang, Wei, Wang, Yu, Xu, Que, Chen, Fan, Ma, Zhou, Huan, Yang, Guo, Chang (CR111) 2023; 24
Hu, Ruan, Ruan, Pei, Jing, Wu, Hou, Xu, Wang, Feng, Zhang (CR99) 2022; 431
Deng, Liu (CR12) 2021; 11
Castilla-Casadiego, Carlton, Gonzalez-Nino, Miranda-Muñoz, Daneshpour, Huitink, Prinz, Powell, Greenlee, Almodovar (CR23) 2021; 118
Liu, Jin, Quan, Kamiyama, Kusamori, Katsumi, Sakane, Yamamoto (CR53) 2014; 86
Chen, Quan, Sun, Yang, Pan, Wu (CR39) 2020; 325
Qian, Ma, Zhao, Guo, Zhang (CR104) 2021; 11
Park, Kim (CR60) 2017; 34
Huh, Kim, Yang, Jang, Kang, Jung (CR82) 2018; 114
Fakhraei Lahiji, Jang, Huh, Yang, Jang, Jung (CR50) 2018; 8
El-Sayed, Vaut, Schneider (CR96) 2020; 154
Zhou, Chen, Yue, Zhang, Huang, Zhao, Wu, Li, Qu, Zhang (CR113) 2021; 609
Kim, Lee, Shayan, Kim, Huh, Ma, Yang, Kang, Jung (CR56) 2018; 180
Leone, Mönkäre, Bouwstra, Kersten (CR83) 2017; 34
Singh, Kesharwani (CR25) 2021; 338
Zhu, Dong, Du, Mao, Xie, Wang, Lan, Lou, Fu, Wen, Jiang, Li, Zhu, Tao (CR57) 2019; 8
Idrees, Zaidi, Sabir, Khan, Zhang, Hassan (CR94) 2020; 10
Salwa, Chevala, Jitta, Marques, Vaz, Kumar (CR19) 2021; 65
Chen, Lai, Ling, Lin (CR65) 2018; 65
Zhou, Tang, Zhang, An, Wu, Tang, Zhou (CR36) 2021; 23
Jing, Ruan, Li, Wang, Pei, Hu, He, Wu, Ruan, Guo, Wang, Feng, Zhang (CR103) 2021; 278
Yang, Xu, Jiang, Chen, Luo, Liu, Qu, Wang, Shan, Cui, Zheng, Wang, Wang, Guo, Li (CR18) 2021; 31
Shen, Lv, Yang, Deng, Liu, Zhou, Zhu, Ma (CR95) 2022; 153
Ono, Ito, Sakagami, Asada, Saito, Quan, Kamiyama, Hirobe, Okada (CR63) 2017; 9
Wang, Zhao, Wu, Tong, Shi, Chen (CR110) 2022; 17
D Huang (39_CR79) 2021; 31
S Bhatnagar (39_CR74) 2018; 8
K K A Altameemi (39_CR97) 2022; 13
X Song (39_CR21) 2021; 63
S Chaudhary (39_CR9) 2019; 51
H Hu (39_CR99) 2022; 431
N El-Sayed (39_CR96) 2020; 154
J Zhu (39_CR57) 2019; 8
N G Oh (39_CR72) 2022; 7
Z Li (39_CR70) 2020; 8
H Du (39_CR54) 2019; 11
J Y Hong (39_CR43) 2018; 17
Z Ahmad (39_CR69) 2020; 21
Z Chen (39_CR40) 2020; 55
T Waghule (39_CR38) 2019; 109
L Liang (39_CR32) 2020; 55
T Guo (39_CR98) 2019; 572
A Khosraviboroujeni (39_CR47) 2022; 12
A Ono (39_CR63) 2017; 9
H T T Nguyen (39_CR11) 2022; 30
N N Aung (39_CR51) 2021; 61
K Lee (39_CR78) 2010; 22
I Huh (39_CR82) 2018; 114
X Lei (39_CR106) 2022; 217
A A Seetharam (39_CR6) 2020; 12
M P Abuçafy (39_CR93) 2018; 127
S Liu (39_CR53) 2014; 86
K Prabahar (39_CR112) 2022; 29
A Hou (39_CR2) 2019; 8
Y Park (39_CR60) 2017; 34
J D Kim (39_CR81) 2013; 170
N Tariq (39_CR26) 2021; 17
S Yao (39_CR107) 2021; 10
S-J Yang (39_CR45) 2021; 201
M-C Chen (39_CR68) 2012; 13
N Elahpour (39_CR30) 2021; 597
Z Deng (39_CR12) 2021; 11
S Kim (39_CR56) 2018; 180
M Zhang (39_CR4) 2022; 14
K Lee (39_CR41) 2011; 32
L Wu (39_CR37) 2021; 61
L Yan (39_CR62) 2014; 3
Y-H Park (39_CR59) 2016; 21
Y Chi (39_CR58) 2022; 168
M J Uddin (39_CR77) 2020; 107
P Zhou (39_CR113) 2021; 609
V Mishra (39_CR35) 2018; 10
C Huang (39_CR102) 2022; 224
H Jung (39_CR15) 2020; 30
L Zhao (39_CR20) 2021; 10
Y Deng (39_CR86) 2020; 7
A D Permana (39_CR109) 2020; X2
C-H Chen (39_CR44) 2018; 11
J W Lee (39_CR64) 2011; 7
M Qian (39_CR104) 2021; 11
H Wang (39_CR110) 2022; 17
S Fakhraei Lahiji (39_CR50) 2018; 8
L Zhang (39_CR75) 2021; 604
G M Pontes-Quero (39_CR88) 2021; 121
Q Jing (39_CR103) 2021; 278
L Shen (39_CR95) 2022; 153
O Howells (39_CR22) 2022; 171
J Yang (39_CR84) 2021; 426
J H Jung (39_CR17) 2021; 51
M-C Chen (39_CR65) 2018; 65
M Dalvi (39_CR27) 2021; 284
H Chang (39_CR85) 2020; 5
H Idrees (39_CR94) 2020; 10
P-T Ko (39_CR24) 2015; 51
J-H Fang (39_CR73) 2020; 12
J Meena (39_CR92) 2020; 18
A D Permana (39_CR108) 2020; 154
Z Zhang (39_CR111) 2023; 24
M-C Chen (39_CR67) 2013; 34
S Hua (39_CR7) 2020; 11
A Sadeqi (39_CR28) 2022; 12
Z U Khan (39_CR89) 2022; 14
C Yiyun (39_CR10) 2007; 96
Q Yan (39_CR49) 2021; 13
K Lee (39_CR80) 2012; 33
L Hadisoewignyo (39_CR5) 2018; 9
L-Y Long (39_CR100) 2022; 14
H Shi (39_CR46) 2022; 18
C Zhou (39_CR36) 2021; 23
X Yang (39_CR105) 2022; 215
R Ye (39_CR33) 2020; 6
K Ita (39_CR76) 2017; 93
R M Shah (39_CR91) 2016; 515
S P Sullivan (39_CR71) 2008; 20
Y Yang (39_CR18) 2021; 31
D Resnik (39_CR34) 2018; 9
M Avcil (39_CR29) 2021; 12
Salwa (39_CR19) 2021; 65
M Leone (39_CR83) 2017; 34
A Raza (39_CR8) 2020; 58
V Singh (39_CR25) 2021; 338
39_CR61
S Jacob (39_CR16) 2021; 13
M Jang (39_CR55) 2020; 42
Y-C Chen (39_CR1) 2021; 330
V Phatale (39_CR13) 2022; 351
A Chandrasekharan (39_CR48) 2019; 11
D A Castilla-Casadiego (39_CR23) 2021; 118
S S Yerneni (39_CR101) 2022; 149
R Feng (39_CR90) 2012; 7
Y Dou (39_CR3) 2020; 327
I De Decker (39_CR42) 2023; 50
S Y Fam (39_CR87) 2020; 10
X Meng (39_CR14) 2020; 30
Y-H Chen (39_CR66) 2019; 97
M Chen (39_CR39) 2020; 325
S Gorantla (39_CR31) 2021; 184
L Dong (39_CR52) 2018; 10
References_xml – volume: 184
  start-page: 438
  year: 2021
  end-page: 453
  ident: CR31
  article-title: Chitosan-based microneedles as a potential platform for drug delivery through the skin: trends and regulatory aspects
  publication-title: Int. J. Biol. Macromol.
– volume: 3
  start-page: 555
  year: 2014
  end-page: 564
  ident: CR62
  article-title: Nanocomposite-strengthened dissolving microneedles for improved transdermal delivery to human skin
  publication-title: Adv. Healthc. Mater.
– volume: 50
  start-page: 422
  year: 2023
  end-page: 444
  ident: CR42
  article-title: Dissolving microneedles for effective and painless intradermal drug delivery in various skin conditions: a systematic review
  publication-title: J. Dermatol.
– volume: 58
  start-page: 101818
  year: 2020
  ident: CR8
  article-title: Zein-based micro- and nano-constructs and biologically therapeutic cues with multi-functionalities for oral drug delivery systems
  publication-title: J. Drug Deliv. Sci. Technol.
– volume: 8
  start-page: e1900898
  year: 2019
  ident: CR2
  article-title: Rational design of rapidly separating dissolving microneedles for precise drug delivery by balancing the mechanical performance and disintegration rate
  publication-title: Adv. Healthc. Mater.
– volume: 18
  start-page: 2107
  year: 2020
  end-page: 2118
  ident: CR92
  article-title: Inorganic nanoparticles for natural product delivery: a review
  publication-title: Environ. Chem. Lett.
– volume: 12
  start-page: 1392
  year: 2020
  ident: CR73
  article-title: Transdermal composite microneedle composed of mesoporous iron oxide nanoraspberry and PVA for androgenetic alopecia treatment
  publication-title: Polymers (Basel)
– volume: 34
  start-page: 2223
  year: 2017
  end-page: 2240
  ident: CR83
  article-title: Dissolving microneedle patches for dermal vaccination
  publication-title: Pharm. Res.
– volume: 217
  start-page: 55
  year: 2022
  end-page: 65
  ident: CR106
  article-title: Degradable microneedle patches loaded with antibacterial gelatin nanoparticles to treat staphylococcal infection-induced chronic wounds
  publication-title: Int. J. Biol. Macromol.
– volume: 13
  start-page: 974
  year: 2022
  end-page: 980
  ident: CR97
  article-title: Anastrozole nanoparticles for transdermal delivery through microneedles: preparation and evaluation
  publication-title: J. Pharm. Negat. Results
– volume: 29
  start-page: 3022
  year: 2022
  end-page: 3034
  ident: CR112
  article-title: Microneedle mediated transdermal delivery of β-sitosterol loaded nanostructured lipid nanoparticles for androgenic alopecia
  publication-title: Drug Deliv.
– volume: 224
  start-page: 111363
  year: 2022
  ident: CR102
  article-title: A novel hyaluronic acid-based dissolving microneedle patch loaded with ginsenoside Rg3 liposome for effectively alleviate psoriasis
  publication-title: Mater. Des.
– volume: 8
  start-page: e1900896
  year: 2019
  ident: CR57
  article-title: 5-aminolevulinic acid-loaded hyaluronic acid dissolving micro-needles for effective photodynamic therapy of superficial tumors with enhanced long-term stability
  publication-title: Adv. Healthc. Mater.
– volume: 8
  start-page: 216
  year: 2020
  end-page: 225
  ident: CR70
  article-title: A fast-dissolving microneedle array loaded with chitosan nanoparticles to evoke systemic immune responses in mice
  publication-title: J. Mater. Chem. B.
– volume: 515
  start-page: 543
  year: 2016
  end-page: 554
  ident: CR91
  article-title: Microwave-assisted formulation of solid lipid nanoparticles loaded with non-steroidal anti-inflammatory drugs
  publication-title: Int. J. Pharm.
– volume: 215
  start-page: 550
  year: 2022
  end-page: 559
  ident: CR105
  article-title: synthesis silver nanoparticles in chitosan polysaccharide composited microneedles for infected and susceptible wound healing
  publication-title: Int. J. Biol. Macromol.
– volume: 17
  start-page: 235
  year: 2018
  end-page: 241
  ident: CR43
  article-title: Efficacy and safety of a novel, soluble microneedle patch for the improvement of facial wrinkle
  publication-title: J. Cosmet. Dermatol.
– volume: 65
  start-page: 66
  year: 2018
  end-page: 75
  ident: CR65
  article-title: Enhancing immunogenicity of antigens through sustained intradermal delivery using chitosan microneedles with a patch-dissolvable design
  publication-title: Acta. Biomater.
– volume: 572
  start-page: 118741
  year: 2019
  ident: CR98
  article-title: Novel nanostructured lipid carriers-loaded dissolving microneedles for controlled local administration of aconitine
  publication-title: Int. J. Pharm.
– volume: 23
  start-page: 2001355
  year: 2021
  ident: CR36
  article-title: Hollow microneedle arrays produced by low-cost, high-fidelity replication of hypodermic needle tips for high-dose transdermal drug delivery
  publication-title: Adv. Eng. Mater.
– volume: 10
  start-page: e2100056
  year: 2021
  ident: CR107
  article-title: Zn-MOF encapsulated antibacterial and degradable microneedles array for promoting wound healing
  publication-title: Adv. Healthc. Mater.
– volume: 170
  start-page: 430
  year: 2013
  end-page: 436
  ident: CR81
  article-title: Droplet-born air blowing: novel dissolving microneedle fabrication
  publication-title: J. Control. Release
– volume: 42
  start-page: 302
  year: 2020
  end-page: 309
  ident: CR55
  article-title: Dissolving microneedle with high molecular weight hyaluronic acid to improve skin wrinkles, dermal density and elasticity
  publication-title: Int. J. Cosmet. Sci.
– volume: 118
  start-page: 111544
  year: 2021
  ident: CR23
  article-title: Design, characterization, and modeling of a chitosan microneedle patch for transdermal delivery of meloxicam as a pain management strategy for use in cattle
  publication-title: Mater. Sci. Eng. C Mater. Biol. Appl.
– volume: 168
  start-page: 106075
  year: 2022
  ident: CR58
  article-title: The effects of molecular weight of hyaluronic acid on transdermal delivery efficiencies of dissolving microneedles
  publication-title: Eur. J. Pharm. Sci.
– volume: 11
  start-page: 1625
  year: 2018
  ident: CR44
  article-title: Dissolving microneedle patches for transdermal insulin delivery in diabetic mice: potential for clinical applications
  publication-title: Materials (Basel)
– volume: 338
  start-page: 394
  year: 2021
  end-page: 409
  ident: CR25
  article-title: Recent advances in microneedles-based drug delivery device in the diagnosis and treatment of cancer
  publication-title: J. Control. Release
– volume: 31
  start-page: 2104092
  year: 2021
  ident: CR18
  article-title: Self-powered controllable transdermal drug delivery system
  publication-title: Adv. Funct. Mater.
– volume: 9
  start-page: 40
  year: 2018
  ident: CR34
  article-title: experimental study of noninvasive insulin microinjection through hollow Si microneedle array
  publication-title: Micromachines (Basel)
– volume: 10
  start-page: 787
  year: 2020
  ident: CR87
  article-title: Stealth coating of nanoparticles in drug- delivery systems
  publication-title: Nanomaterials (Basel)
– volume: 10
  start-page: e2100996
  year: 2021
  ident: CR20
  article-title: Smart responsive microarray patches for transdermal drug delivery and biological monitoring
  publication-title: Adv. Healthc. Mater.
– volume: 51
  start-page: 503
  year: 2021
  end-page: 517
  ident: CR17
  article-title: Microneedle for transdermal drug delivery: current trends and fabrication
  publication-title: J. Pharm. Investig.
– volume: 21
  start-page: 110
  year: 2016
  end-page: 118
  ident: CR59
  article-title: Fabrication of degradable carboxymethyl cellulose (CMC) microneedle with laser writing and replica molding process for enhancement of transdermal drug delivery
  publication-title: Biotechnol. Bioprocess Eng.
– volume: 11
  start-page: 1475
  year: 2021
  end-page: 1497
  ident: CR12
  article-title: Inflammation-responsive delivery systems for the treatment of chronic inflammatory diseases
  publication-title: Drug Deliv. Transi. Res.
– volume: 55
  start-page: 101464
  year: 2020
  ident: CR32
  article-title: Optimization of dip-coating methods for the fabrication of coated microneedles for drug delivery
  publication-title: J. Drug Deliv. Sci. Technol.
– volume: 114
  start-page: 285
  year: 2018
  end-page: 292
  ident: CR82
  article-title: Effects of two droplet-based dissolving microneedle manufacturing methods on the activity of encapsulated epidermal growth factor and ascorbic acid
  publication-title: Eur. J. Pharm. Sci.
– volume: X2
  start-page: 100047
  year: 2020
  ident: CR109
  article-title: Bacterially sensitive nanoparticle-based dissolving microneedles of doxycycline for enhanced treatment of bacterial biofilm skin infection: a proof of concept study
  publication-title: Int. J. Pharm.
– volume: 351
  start-page: 361
  year: 2022
  end-page: 380
  ident: CR13
  article-title: Overcoming skin barriers through advanced transdermal drug delivery approaches
  publication-title: J. Control Release
– volume: 10
  start-page: 1970
  year: 2020
  ident: CR94
  article-title: A review of biodegradable natural polymer-based nanoparticles for drug delivery applications
  publication-title: Nanomaterials (Basel)
– volume: 330
  start-page: 438
  year: 2021
  end-page: 460
  ident: CR1
  article-title: Local drug delivery systems for inflammatory diseases: Status quo, challenges, and opportunities
  publication-title: J. Control. Release
– volume: 8
  start-page: 473
  year: 2018
  end-page: 483
  ident: CR74
  article-title: Corneal delivery of besifloxacin using rapidly dissolving polymeric microneedles
  publication-title: Drug Deliv. Transl. Res.
– volume: 11
  start-page: 524
  year: 2020
  ident: CR7
  article-title: Advances in oral drug delivery for regional targeting in the gastrointestinal tract - influence of physiological, pathophysiological and pharmaceutical factors
  publication-title: Front. Pharmacol.
– volume: 14
  start-page: 100223
  year: 2022
  ident: CR4
  article-title: Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment
  publication-title: Mater. Today Bio.
– volume: 11
  start-page: 1101
  year: 2021
  end-page: 1108
  ident: CR104
  article-title: A novel fast-releasing formulation containing curcumin and antimicrobial peptide-encapsulated transdermal hydrogels into microneedles to reduce inflammation in the therapy of neonatal sepsis
  publication-title: Mater. Express
– volume: 86
  start-page: 267
  year: 2014
  end-page: 276
  ident: CR53
  article-title: Transdermal delivery of relatively high molecular weight drugs using novel self-dissolving microneedle arrays fabricated from hyaluronic acid and their characteristics and safety after application to the skin
  publication-title: Eur. J. Pharm. Biopharm.
– volume: 12
  start-page: 1101
  year: 2020
  ident: CR6
  article-title: Microneedles drug delivery systems for treatment of cancer: a recent update
  publication-title: Pharmaceutics
– volume: 12
  start-page: 1321
  year: 2021
  ident: CR29
  article-title: Microneedles in drug delivery: progress and challenges
  publication-title: Micromachines (Basel)
– volume: 12
  start-page: 1195
  year: 2022
  end-page: 1208
  ident: CR47
  article-title: Preparation and characterization of 3D printed PLA microneedle arrays for prolonged transdermal drug delivery of estradiol valerate
  publication-title: Drug Deliv. Transl. Res.
– volume: 14
  start-page: 409
  year: 2022
  ident: CR89
  article-title: Physicochemical characterizations and pharmacokinetic evaluation of pentazocine solid lipid nanoparticles against inflammatory pain model
  publication-title: Pharmaceutics
– volume: 8
  start-page: 1170
  year: 2018
  ident: CR50
  article-title: Exendin-4–encapsulated dissolving microneedle arrays for efficient treatment of type 2 diabetes
  publication-title: Sci. Rep.
– volume: 7
  start-page: 489
  year: 2020
  ident: CR86
  article-title: Application of the nano-drug delivery system in treatment of cardiovascular diseases
  publication-title: Front. Bioeng. Biotechnol.
– volume: 11
  start-page: 43588
  year: 2019
  end-page: 43598
  ident: CR54
  article-title: Hyaluronic acid-based dissolving microneedle patch loaded with methotrexate for improved treatment of psoriasis
  publication-title: ACS Appl. Mater. Interfaces
– volume: 327
  start-page: 641
  year: 2020
  end-page: 666
  ident: CR3
  article-title: Bioresponsive drug delivery systems for the treatment of inflammatory diseases
  publication-title: J. Control. Release
– volume: 11
  start-page: 209
  year: 2019
  ident: CR48
  article-title: Acid-treated water-soluble chitosan suitable for microneedle-assisted intracutaneous drug delivery
  publication-title: Pharmaceutics
– volume: 34
  start-page: 133
  year: 2017
  end-page: 138
  ident: CR60
  article-title: Skin permeability of compounds loaded within dissolving microneedles dependent on composition of sodium hyaluronate and carboxymethyl cellulose
  publication-title: Korean. J. Chem. Eng.
– volume: 13
  start-page: 4022
  year: 2012
  end-page: 4031
  ident: CR68
  article-title: Chitosan microneedle patches for sustained transdermal delivery of macromolecules
  publication-title: Biomacromolecules
– volume: 93
  start-page: 1116
  year: 2017
  end-page: 1127
  ident: CR76
  article-title: Dissolving microneedles for transdermal drug delivery: advances and challenges
  publication-title: Biomed. Pharmacother.
– volume: 107
  start-page: 110248
  year: 2020
  ident: CR77
  article-title: 3D printed microneedles for anticancer therapy of skin tumours
  publication-title: Mater. Sci. Eng. C Mater. Biol. Appl.
– ident: CR61
– volume: 9
  start-page: 27
  year: 2017
  ident: CR63
  article-title: Development of novel faster-dissolving microneedle patches for transcutaneous vaccine delivery
  publication-title: Pharmaceutics
– volume: 154
  start-page: 166
  year: 2020
  end-page: 174
  ident: CR96
  article-title: Customized fast-separable microneedles prepared with the aid of 3D printing for nanoparticle delivery
  publication-title: Eur. J. Pharm. Biopharm.
– volume: 24
  start-page: 81
  year: 2023
  end-page: 95
  ident: CR111
  article-title: A combination therapy for androgenic alopecia based on quercetin and zinc/copper dual-doped mesoporous silica nanocomposite microneedle patch
  publication-title: Bioact. Mater.
– volume: 34
  start-page: 3077
  year: 2013
  end-page: 3086
  ident: CR67
  article-title: Fully embeddable chitosan microneedles as a sustained release depot for intradermal vaccination
  publication-title: Biomaterials
– volume: 609
  start-page: 121211
  year: 2021
  ident: CR113
  article-title: Strategy for osteoarthritis therapy: Improved the delivery of triptolide using liposome-loaded dissolving microneedle arrays
  publication-title: Int. J. Pharm.
– volume: 21
  start-page: 68
  year: 2020
  ident: CR69
  article-title: Fabrication and characterization of thiolated chitosan microneedle patch for transdermal delivery of tacrolimus
  publication-title: AAPS PharmSciTech.
– volume: 32
  start-page: 3134
  year: 2011
  end-page: 3140
  ident: CR41
  article-title: Dissolving microneedles for transdermal drug administration prepared by stepwise controlled drawing of maltose
  publication-title: Biomaterials
– volume: 30
  start-page: 2004407
  year: 2020
  ident: CR15
  article-title: Adhesive hydrogel patch with enhanced strength and adhesiveness to skin for transdermal drug delivery
  publication-title: Adv. Funct. Mater.
– volume: 180
  start-page: 297
  year: 2018
  end-page: 303
  ident: CR56
  article-title: Physicochemical study of ascorbic acid 2-glucoside loaded hyaluronic acid dissolving microneedles irradiated by electron beam and gamma ray
  publication-title: Carbohydr. Polym.
– volume: 96
  start-page: 595
  year: 2007
  end-page: 602
  ident: CR10
  article-title: Transdermal delivery of nonsteroidal anti-inflammatory drugs mediated by polyamidoamine (PAMAM) dendrimers
  publication-title: J. Pharm. Sci.
– volume: 431
  start-page: 134196
  year: 2022
  ident: CR99
  article-title: Acid-responsive PEGylated branching PLGA nanoparticles integrated into dissolving microneedles enhance local treatment of arthritis
  publication-title: Chem. Eng. J.
– volume: 7
  start-page: 4089
  year: 2012
  end-page: 4098
  ident: CR90
  article-title: Preparation and pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles
  publication-title: Int. J. Nanomedicine
– volume: 109
  start-page: 1249
  year: 2019
  end-page: 1258
  ident: CR38
  article-title: Microneedles: a smart approach and increasing potential for transdermal drug delivery system
  publication-title: Biomed. Pharmacother.
– volume: 18
  start-page: e2104657
  year: 2022
  ident: CR46
  article-title: A rapid corneal healing microneedle for efficient ocular drug delivery
  publication-title: Small
– volume: 20
  start-page: 933
  year: 2008
  end-page: 938
  ident: CR71
  article-title: Minimally invasive protein delivery with rapidly dissolving polymer microneedles
  publication-title: Adv. Mater.
– volume: 325
  start-page: 163
  year: 2020
  end-page: 175
  ident: CR39
  article-title: Nanoparticles-encapsulated polymeric microneedles for transdermal drug delivery
  publication-title: J. Control. Release
– volume: 55
  start-page: 101487
  year: 2020
  ident: CR40
  article-title: Enhanced transdermal delivery of polydatin via a combination of inclusion complexes and dissolving micro-needles for treatment of acute gout arthritis
  publication-title: J. Drug Deliv. Sci. Technol.
– volume: 426
  start-page: 130561
  year: 2021
  ident: CR84
  article-title: Recent advances of microneedles used towards stimuli-responsive drug delivery, disease theranostics, and bioinspired applications
  publication-title: Chem. Eng. J.
– volume: 284
  start-page: 119877
  year: 2021
  ident: CR27
  article-title: Panorama of dissolving microneedles for transdermal drug delivery
  publication-title: Life Sci.
– volume: 65
  start-page: 102711
  year: 2021
  ident: CR19
  article-title: Polymeric microneedles for transdermal delivery of nanoparticles: frontiers of formulation, sterility and stability aspects
  publication-title: J. Drug Deliv. Sci. Technol.
– volume: 5
  start-page: 1900552
  year: 2020
  ident: CR85
  article-title: Advances in the formulations of microneedles for manifold biomedical applications
  publication-title: Adv. Mater. Technol.
– volume: 7
  start-page: 25179
  year: 2022
  end-page: 25185
  ident: CR72
  article-title: Fabrication of a PVA-based hydrogel microneedle patch
  publication-title: ACS Omega.
– volume: 153
  start-page: 113492
  year: 2022
  ident: CR95
  article-title: Bufotenines-loaded liposome exerts anti-inflammatory, analgesic effects and reduce gastrointestinal toxicity through altering lipid and bufotenines metabolism
  publication-title: Biomed. Pharmacother.
– volume: 30
  start-page: 589
  year: 2020
  end-page: 596
  ident: CR14
  article-title: Micro/nano needles for advanced drug delivery
  publication-title: Prog. Nat. Sci.
– volume: 17
  start-page: 1464
  year: 2021
  end-page: 1483
  ident: CR26
  article-title: A review on solid microneedles for biomedical applications
  publication-title: J. Pharm. Innov.
– volume: 22
  start-page: 483
  year: 2010
  end-page: 486
  ident: CR78
  article-title: Drawing lithography: three-dimensional fabrication of an ultrahigh-aspect-ratio microneedle
  publication-title: Adv. Mater.
– volume: 597
  start-page: 120301
  year: 2021
  ident: CR30
  article-title: 3D printed microneedles for transdermal drug delivery: a brief review of two decades
  publication-title: Int. J. Pharm.
– volume: 61
  start-page: 102284
  year: 2021
  ident: CR51
  article-title: Enhancement of transdermal delivery of resveratrol using Eudragit and polyvinyl pyrrolidone-based dissolving microneedle patches
  publication-title: J. Drug Deliv. Sci. Technol.
– volume: 7
  start-page: 531
  year: 2011
  end-page: 539
  ident: CR64
  article-title: Dissolving microneedle patch for transdermal delivery of human growth hormone
  publication-title: Small
– volume: 30
  start-page: 655
  year: 2022
  end-page: 670
  ident: CR11
  article-title: Synthesis, properties, and applications of chitosan hydrogels as anti-inflammatory drug delivery system
  publication-title: J. Porous. Mater.
– volume: 61
  start-page: 102192
  year: 2021
  ident: CR37
  article-title: Characterization method for calculating diffusion coefficient of drug from polylactic acid (PLA) microneedles into the skin
  publication-title: J. Drug Deliv. Sci. Technol.
– volume: 278
  start-page: 121142
  year: 2021
  ident: CR103
  article-title: Keratinocyte membrane-mediated nanodelivery system with dissolving microneedles for targeted therapy of skin diseases
  publication-title: Biomaterials
– volume: 604
  start-page: 120749
  year: 2021
  ident: CR75
  article-title: Fabrication, evaluation and applications of dissolving microneedles
  publication-title: Int. J. Pharm.
– volume: 149
  start-page: 198
  year: 2022
  end-page: 212
  ident: CR101
  article-title: Skin-targeted delivery of extracellular vesicle-encapsulated curcumin using dissolvable microneedle arrays
  publication-title: Acta. Biomater.
– volume: 33
  start-page: 7309
  year: 2012
  end-page: 7326
  ident: CR80
  article-title: Drawing lithography for microneedles: a review of fundamentals and biomedical applications
  publication-title: Biomaterials
– volume: 121
  start-page: 111793
  year: 2021
  ident: CR88
  article-title: Amphiphilic polymeric nanoparticles encapsulating curcumin: antioxidant, anti-inflammatory and biocompatibility studies
  publication-title: Mater. Sci. Eng. C Mater. Biol. Appl.
– volume: 13
  start-page: 357
  year: 2021
  ident: CR16
  article-title: Emerging role of hydrogels in drug delivery systems, tissue engineering and wound management
  publication-title: Pharmaceutics
– volume: 51
  start-page: 1
  year: 2015
  end-page: 8
  ident: CR24
  article-title: Polymer microneedles fabricated from PCL and PCL/PEG blends for transdermal delivery of hydrophilic compounds
  publication-title: J. Taiwan Inst. Chem. Eng.
– volume: 13
  start-page: 3043
  year: 2021
  ident: CR49
  article-title: Finite element analysis for biodegradable dissolving microneedle materials on skin puncture and mechanical performance evaluation
  publication-title: Polymers (Basel)
– volume: 154
  start-page: 50
  year: 2020
  end-page: 61
  ident: CR108
  article-title: Dissolving microneedle-mediated dermal delivery of itraconazole nanocrystals for improved treatment of cutaneous candidiasis
  publication-title: Eur. J. Pharm. Biopharm.
– volume: 31
  start-page: 073001
  year: 2021
  ident: CR79
  article-title: Recent advances on fabrication of microneedles on the flexible substrate
  publication-title: J. Micromech. Microeng.
– volume: 10
  start-page: 9247
  year: 2018
  end-page: 9256
  ident: CR52
  article-title: Au nanocage-strengthened dissolving microneedles for chemo-photothermal combined therapy of superficial skin tumors
  publication-title: ACS Appl. Mater. Interfaces
– volume: 97
  start-page: 230
  year: 2019
  end-page: 238
  ident: CR66
  article-title: Implantable microneedles with an immune-boosting function for effective intradermal influenza vaccination
  publication-title: Acta. Biomater.
– volume: 51
  start-page: 736
  year: 2019
  end-page: 745
  ident: CR9
  article-title: Self-nanoemulsifying drug delivery system of nabumetone improved its oral bioavailability and anti-inflammatory effects in rat model
  publication-title: J. Drug Deliv. Sci. Technol.
– volume: 12
  start-page: 1853
  year: 2022
  ident: CR28
  article-title: Hard polymeric porous microneedles on stretchable substrate for transdermal drug delivery
  publication-title: Sci. Rep.
– volume: 63
  start-page: 102537
  year: 2021
  ident: CR21
  article-title: Dosage-efficacy relationship and pharmacodynamics validation of brucine dissolving microneedles against rheumatoid arthritis
  publication-title: J. Drug Deliv. Sci. Technol.
– volume: 17
  start-page: 3841
  year: 2022
  end-page: 3851
  ident: CR110
  article-title: Microneedle patch delivery of methotrexate-loaded albumin nanoparticles to immune cells achieves a potent antipsoriatic effect
  publication-title: Int. J. Nanomedicine.
– volume: 171
  start-page: 19
  year: 2022
  end-page: 28
  ident: CR22
  article-title: Design, fabrication, and characterisation of a silicon microneedle array for transdermal therapeutic delivery using a single step wet etch process
  publication-title: Eur. J. Pharm. Biopharm.
– volume: 9
  start-page: 035007
  year: 2018
  ident: CR5
  article-title: Evaluation of anti-inflammatory activity and biocompatibility of curcumin loaded mesoporous silica nanoparticles as an oral drug delivery system
  publication-title: Adv. Nat. Sci: Nanosci. Nanotechnol.
– volume: 201
  start-page: 109485
  year: 2021
  ident: CR45
  article-title: Synthesis and characterization of PVP microneedle patch using metal bioelectrodes for novel drug delivery system
  publication-title: Mater. Des.
– volume: 127
  start-page: 112
  year: 2018
  end-page: 119
  ident: CR93
  article-title: Supramolecular cyclodextrin-based metal-organic frameworks as efficient carrier for anti-inflammatory drugs
  publication-title: Eur. J. Pharm. Biopharm.
– volume: 6
  start-page: 2487
  year: 2020
  end-page: 2494
  ident: CR33
  article-title: Fabrication of tip-hollow and tip-dissolvable microneedle arrays for transdermal drug delivery
  publication-title: ACS Biomater. Sci. Eng.
– volume: 10
  start-page: 191
  year: 2018
  ident: CR35
  article-title: Solid lipid nanoparticles: emerging colloidal nano drug delivery systems
  publication-title: Pharmaceutics
– volume: 14
  start-page: 1285
  year: 2022
  end-page: 1295
  ident: CR100
  article-title: Dissolving microneedle-encapsulated drug-loaded nanoparticles and recombinant humanized collagen type III for the treatment of chronic wound via antiinflammation and enhanced cell proliferation and angiogenesis
  publication-title: Nanoscale
– volume: 3
  start-page: 555
  year: 2014
  ident: 39_CR62
  publication-title: Adv. Healthc. Mater.
  doi: 10.1002/adhm.201300312
– volume: 21
  start-page: 68
  year: 2020
  ident: 39_CR69
  publication-title: AAPS PharmSciTech.
  doi: 10.1208/s12249-019-1611-9
– volume: 65
  start-page: 102711
  year: 2021
  ident: 39_CR19
  publication-title: J. Drug Deliv. Sci. Technol.
  doi: 10.1016/j.jddst.2021.102711
– volume: 14
  start-page: 1285
  year: 2022
  ident: 39_CR100
  publication-title: Nanoscale
  doi: 10.1039/D1NR07708B
– volume: 18
  start-page: e2104657
  year: 2022
  ident: 39_CR46
  publication-title: Small
  doi: 10.1002/smll.202104657
– volume: 154
  start-page: 50
  year: 2020
  ident: 39_CR108
  publication-title: Eur. J. Pharm. Biopharm.
  doi: 10.1016/j.ejpb.2020.06.025
– volume: 180
  start-page: 297
  year: 2018
  ident: 39_CR56
  publication-title: Carbohydr. Polym.
  doi: 10.1016/j.carbpol.2017.10.044
– volume: 61
  start-page: 102284
  year: 2021
  ident: 39_CR51
  publication-title: J. Drug Deliv. Sci. Technol.
  doi: 10.1016/j.jddst.2020.102284
– volume: 431
  start-page: 134196
  year: 2022
  ident: 39_CR99
  publication-title: Chem. Eng. J.
  doi: 10.1016/j.cej.2021.134196
– volume: 330
  start-page: 438
  year: 2021
  ident: 39_CR1
  publication-title: J. Control. Release
  doi: 10.1016/j.jconrel.2020.12.025
– volume: 10
  start-page: 9247
  year: 2018
  ident: 39_CR52
  publication-title: ACS Appl. Mater. Interfaces
  doi: 10.1021/acsami.7b18293
– volume: 217
  start-page: 55
  year: 2022
  ident: 39_CR106
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2022.07.021
– volume: 18
  start-page: 2107
  year: 2020
  ident: 39_CR92
  publication-title: Environ. Chem. Lett.
  doi: 10.1007/s10311-020-01061-2
– volume: 14
  start-page: 100223
  year: 2022
  ident: 39_CR4
  publication-title: Mater. Today Bio.
  doi: 10.1016/j.mtbio.2022.100223
– volume: 23
  start-page: 2001355
  year: 2021
  ident: 39_CR36
  publication-title: Adv. Eng. Mater.
  doi: 10.1002/adem.202001355
– volume: 11
  start-page: 43588
  year: 2019
  ident: 39_CR54
  publication-title: ACS Appl. Mater. Interfaces
  doi: 10.1021/acsami.9b15668
– volume: 30
  start-page: 2004407
  year: 2020
  ident: 39_CR15
  publication-title: Adv. Funct. Mater.
  doi: 10.1002/adfm.202004407
– volume: 11
  start-page: 1625
  year: 2018
  ident: 39_CR44
  publication-title: Materials (Basel)
  doi: 10.3390/ma11091625
– volume: 168
  start-page: 106075
  year: 2022
  ident: 39_CR58
  publication-title: Eur. J. Pharm. Sci.
  doi: 10.1016/j.ejps.2021.106075
– volume: 109
  start-page: 1249
  year: 2019
  ident: 39_CR38
  publication-title: Biomed. Pharmacother.
  doi: 10.1016/j.biopha.2018.10.078
– volume: 7
  start-page: 4089
  year: 2012
  ident: 39_CR90
  publication-title: Int. J. Nanomedicine
  doi: 10.2147/IJN.S33607
– volume: X2
  start-page: 100047
  year: 2020
  ident: 39_CR109
  publication-title: Int. J. Pharm.
– volume: 34
  start-page: 3077
  year: 2013
  ident: 39_CR67
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2012.12.041
– volume: 597
  start-page: 120301
  year: 2021
  ident: 39_CR30
  publication-title: Int. J. Pharm.
  doi: 10.1016/j.ijpharm.2021.120301
– volume: 13
  start-page: 3043
  year: 2021
  ident: 39_CR49
  publication-title: Polymers (Basel)
  doi: 10.3390/polym13183043
– volume: 327
  start-page: 641
  year: 2020
  ident: 39_CR3
  publication-title: J. Control. Release
  doi: 10.1016/j.jconrel.2020.09.008
– volume: 7
  start-page: 531
  year: 2011
  ident: 39_CR64
  publication-title: Small
  doi: 10.1002/smll.201001091
– volume: 572
  start-page: 118741
  year: 2019
  ident: 39_CR98
  publication-title: Int. J. Pharm.
  doi: 10.1016/j.ijpharm.2019.118741
– volume: 118
  start-page: 111544
  year: 2021
  ident: 39_CR23
  publication-title: Mater. Sci. Eng. C Mater. Biol. Appl.
  doi: 10.1016/j.msec.2020.111544
– volume: 8
  start-page: 473
  year: 2018
  ident: 39_CR74
  publication-title: Drug Deliv. Transl. Res.
  doi: 10.1007/s13346-017-0470-8
– volume: 22
  start-page: 483
  year: 2010
  ident: 39_CR78
  publication-title: Adv. Mater.
  doi: 10.1002/adma.200902418
– volume: 96
  start-page: 595
  year: 2007
  ident: 39_CR10
  publication-title: J. Pharm. Sci.
  doi: 10.1002/jps.20745
– volume: 7
  start-page: 489
  year: 2020
  ident: 39_CR86
  publication-title: Front. Bioeng. Biotechnol.
  doi: 10.3389/fbioe.2019.00489
– volume: 114
  start-page: 285
  year: 2018
  ident: 39_CR82
  publication-title: Eur. J. Pharm. Sci.
  doi: 10.1016/j.ejps.2017.12.025
– volume: 325
  start-page: 163
  year: 2020
  ident: 39_CR39
  publication-title: J. Control. Release
  doi: 10.1016/j.jconrel.2020.06.039
– volume: 32
  start-page: 3134
  year: 2011
  ident: 39_CR41
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2011.01.014
– volume: 12
  start-page: 1392
  year: 2020
  ident: 39_CR73
  publication-title: Polymers (Basel)
  doi: 10.3390/polym12061392
– volume: 12
  start-page: 1321
  year: 2021
  ident: 39_CR29
  publication-title: Micromachines (Basel)
  doi: 10.3390/mi12111321
– volume: 9
  start-page: 27
  year: 2017
  ident: 39_CR63
  publication-title: Pharmaceutics
  doi: 10.3390/pharmaceutics9030027
– volume: 29
  start-page: 3022
  year: 2022
  ident: 39_CR112
  publication-title: Drug Deliv.
  doi: 10.1080/10717544.2022.2120927
– volume: 284
  start-page: 119877
  year: 2021
  ident: 39_CR27
  publication-title: Life Sci.
  doi: 10.1016/j.lfs.2021.119877
– volume: 34
  start-page: 133
  year: 2017
  ident: 39_CR60
  publication-title: Korean. J. Chem. Eng.
  doi: 10.1007/s11814-016-0240-1
– volume: 65
  start-page: 66
  year: 2018
  ident: 39_CR65
  publication-title: Acta. Biomater.
  doi: 10.1016/j.actbio.2017.11.004
– volume: 153
  start-page: 113492
  year: 2022
  ident: 39_CR95
  publication-title: Biomed. Pharmacother.
  doi: 10.1016/j.biopha.2022.113492
– volume: 224
  start-page: 111363
  year: 2022
  ident: 39_CR102
  publication-title: Mater. Des.
  doi: 10.1016/j.matdes.2022.111363
– volume: 51
  start-page: 736
  year: 2019
  ident: 39_CR9
  publication-title: J. Drug Deliv. Sci. Technol.
  doi: 10.1016/j.jddst.2018.04.009
– volume: 154
  start-page: 166
  year: 2020
  ident: 39_CR96
  publication-title: Eur. J. Pharm. Biopharm.
  doi: 10.1016/j.ejpb.2020.07.005
– volume: 9
  start-page: 035007
  year: 2018
  ident: 39_CR5
  publication-title: Adv. Nat. Sci: Nanosci. Nanotechnol.
– volume: 11
  start-page: 524
  year: 2020
  ident: 39_CR7
  publication-title: Front. Pharmacol.
  doi: 10.3389/fphar.2020.00524
– volume: 17
  start-page: 235
  year: 2018
  ident: 39_CR43
  publication-title: J. Cosmet. Dermatol.
  doi: 10.1111/jocd.12426
– volume: 24
  start-page: 81
  year: 2023
  ident: 39_CR111
  publication-title: Bioact. Mater.
  doi: 10.1016/j.bioactmat.2022.12.007
– volume: 55
  start-page: 101464
  year: 2020
  ident: 39_CR32
  publication-title: J. Drug Deliv. Sci. Technol.
  doi: 10.1016/j.jddst.2019.101464
– volume: 426
  start-page: 130561
  year: 2021
  ident: 39_CR84
  publication-title: Chem. Eng. J.
  doi: 10.1016/j.cej.2021.130561
– volume: 21
  start-page: 110
  year: 2016
  ident: 39_CR59
  publication-title: Biotechnol. Bioprocess Eng.
  doi: 10.1007/s12257-015-0634-7
– volume: 8
  start-page: 1170
  year: 2018
  ident: 39_CR50
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-018-19789-x
– volume: 12
  start-page: 1853
  year: 2022
  ident: 39_CR28
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-022-05912-6
– volume: 515
  start-page: 543
  year: 2016
  ident: 39_CR91
  publication-title: Int. J. Pharm.
  doi: 10.1016/j.ijpharm.2016.10.054
– volume: 13
  start-page: 357
  year: 2021
  ident: 39_CR16
  publication-title: Pharmaceutics
  doi: 10.3390/pharmaceutics13030357
– volume: 11
  start-page: 209
  year: 2019
  ident: 39_CR48
  publication-title: Pharmaceutics
  doi: 10.3390/pharmaceutics11050209
– volume: 604
  start-page: 120749
  year: 2021
  ident: 39_CR75
  publication-title: Int. J. Pharm.
  doi: 10.1016/j.ijpharm.2021.120749
– volume: 63
  start-page: 102537
  year: 2021
  ident: 39_CR21
  publication-title: J. Drug Deliv. Sci. Technol.
  doi: 10.1016/j.jddst.2021.102537
– volume: 17
  start-page: 1464
  year: 2021
  ident: 39_CR26
  publication-title: J. Pharm. Innov.
  doi: 10.1007/s12247-021-09586-x
– volume: 7
  start-page: 25179
  year: 2022
  ident: 39_CR72
  publication-title: ACS Omega.
  doi: 10.1021/acsomega.2c01993
– volume: 51
  start-page: 1
  year: 2015
  ident: 39_CR24
  publication-title: J. Taiwan Inst. Chem. Eng.
  doi: 10.1016/j.jtice.2015.01.003
– volume: 97
  start-page: 230
  year: 2019
  ident: 39_CR66
  publication-title: Acta. Biomater.
  doi: 10.1016/j.actbio.2019.07.048
– volume: 31
  start-page: 2104092
  year: 2021
  ident: 39_CR18
  publication-title: Adv. Funct. Mater.
  doi: 10.1002/adfm.202104092
– volume: 20
  start-page: 933
  year: 2008
  ident: 39_CR71
  publication-title: Adv. Mater.
  doi: 10.1002/adma.200701205
– volume: 10
  start-page: 1970
  year: 2020
  ident: 39_CR94
  publication-title: Nanomaterials (Basel)
  doi: 10.3390/nano10101970
– volume: 10
  start-page: 191
  year: 2018
  ident: 39_CR35
  publication-title: Pharmaceutics
  doi: 10.3390/pharmaceutics10040191
– volume: 55
  start-page: 101487
  year: 2020
  ident: 39_CR40
  publication-title: J. Drug Deliv. Sci. Technol.
  doi: 10.1016/j.jddst.2019.101487
– volume: 93
  start-page: 1116
  year: 2017
  ident: 39_CR76
  publication-title: Biomed. Pharmacother.
  doi: 10.1016/j.biopha.2017.07.019
– volume: 8
  start-page: 216
  year: 2020
  ident: 39_CR70
  publication-title: J. Mater. Chem. B.
  doi: 10.1039/C9TB02061F
– volume: 609
  start-page: 121211
  year: 2021
  ident: 39_CR113
  publication-title: Int. J. Pharm.
  doi: 10.1016/j.ijpharm.2021.121211
– volume: 8
  start-page: e1900898
  year: 2019
  ident: 39_CR2
  publication-title: Adv. Healthc. Mater.
  doi: 10.1002/adhm.201900898
– volume: 30
  start-page: 655
  year: 2022
  ident: 39_CR11
  publication-title: J. Porous. Mater.
  doi: 10.1007/s10934-022-01371-6
– volume: 12
  start-page: 1195
  year: 2022
  ident: 39_CR47
  publication-title: Drug Deliv. Transl. Res.
  doi: 10.1007/s13346-021-01006-4
– volume: 11
  start-page: 1475
  year: 2021
  ident: 39_CR12
  publication-title: Drug Deliv. Transi. Res.
  doi: 10.1007/s13346-021-00977-8
– volume: 9
  start-page: 40
  year: 2018
  ident: 39_CR34
  publication-title: Micromachines (Basel)
  doi: 10.3390/mi9010040
– volume: 42
  start-page: 302
  year: 2020
  ident: 39_CR55
  publication-title: Int. J. Cosmet. Sci.
  doi: 10.1111/ics.12617
– volume: 10
  start-page: e2100056
  year: 2021
  ident: 39_CR107
  publication-title: Adv. Healthc. Mater.
  doi: 10.1002/adhm.202100056
– volume: 6
  start-page: 2487
  year: 2020
  ident: 39_CR33
  publication-title: ACS Biomater. Sci. Eng.
  doi: 10.1021/acsbiomaterials.0c00120
– volume: 33
  start-page: 7309
  year: 2012
  ident: 39_CR80
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2012.06.065
– volume: 215
  start-page: 550
  year: 2022
  ident: 39_CR105
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2022.06.131
– volume: 61
  start-page: 102192
  year: 2021
  ident: 39_CR37
  publication-title: J. Drug Deliv. Sci. Technol.
  doi: 10.1016/j.jddst.2020.102192
– volume: 30
  start-page: 589
  year: 2020
  ident: 39_CR14
  publication-title: Prog. Nat. Sci.
  doi: 10.1016/j.pnsc.2020.09.016
– volume: 121
  start-page: 111793
  year: 2021
  ident: 39_CR88
  publication-title: Mater. Sci. Eng. C Mater. Biol. Appl.
  doi: 10.1016/j.msec.2020.111793
– volume: 5
  start-page: 1900552
  year: 2020
  ident: 39_CR85
  publication-title: Adv. Mater. Technol.
  doi: 10.1002/admt.201900552
– volume: 8
  start-page: e1900896
  year: 2019
  ident: 39_CR57
  publication-title: Adv. Healthc. Mater.
  doi: 10.1002/adhm.201900896
– volume: 351
  start-page: 361
  year: 2022
  ident: 39_CR13
  publication-title: J. Control Release
  doi: 10.1016/j.jconrel.2022.09.025
– volume: 107
  start-page: 110248
  year: 2020
  ident: 39_CR77
  publication-title: Mater. Sci. Eng. C Mater. Biol. Appl.
  doi: 10.1016/j.msec.2019.110248
– volume: 10
  start-page: e2100996
  year: 2021
  ident: 39_CR20
  publication-title: Adv. Healthc. Mater.
  doi: 10.1002/adhm.202100996
– volume: 86
  start-page: 267
  year: 2014
  ident: 39_CR53
  publication-title: Eur. J. Pharm. Biopharm.
  doi: 10.1016/j.ejpb.2013.10.001
– volume: 127
  start-page: 112
  year: 2018
  ident: 39_CR93
  publication-title: Eur. J. Pharm. Biopharm.
  doi: 10.1016/j.ejpb.2018.02.009
– volume: 11
  start-page: 1101
  year: 2021
  ident: 39_CR104
  publication-title: Mater. Express
  doi: 10.1166/mex.2021.1893
– volume: 184
  start-page: 438
  year: 2021
  ident: 39_CR31
  publication-title: Int. J. Biol. Macromol.
  doi: 10.1016/j.ijbiomac.2021.06.059
– volume: 17
  start-page: 3841
  year: 2022
  ident: 39_CR110
  publication-title: Int. J. Nanomedicine.
  doi: 10.2147/IJN.S371183
– ident: 39_CR61
  doi: 10.1007/s12247-022-09670-w
– volume: 31
  start-page: 073001
  year: 2021
  ident: 39_CR79
  publication-title: J. Micromech. Microeng.
  doi: 10.1088/1361-6439/ac0513
– volume: 50
  start-page: 422
  year: 2023
  ident: 39_CR42
  publication-title: J. Dermatol.
  doi: 10.1111/1346-8138.16732
– volume: 170
  start-page: 430
  year: 2013
  ident: 39_CR81
  publication-title: J. Control. Release
  doi: 10.1016/j.jconrel.2013.05.026
– volume: 51
  start-page: 503
  year: 2021
  ident: 39_CR17
  publication-title: J. Pharm. Investig.
  doi: 10.1007/s40005-021-00512-4
– volume: 278
  start-page: 121142
  year: 2021
  ident: 39_CR103
  publication-title: Biomaterials
  doi: 10.1016/j.biomaterials.2021.121142
– volume: 171
  start-page: 19
  year: 2022
  ident: 39_CR22
  publication-title: Eur. J. Pharm. Biopharm.
  doi: 10.1016/j.ejpb.2021.06.005
– volume: 10
  start-page: 787
  year: 2020
  ident: 39_CR87
  publication-title: Nanomaterials (Basel)
  doi: 10.3390/nano10040787
– volume: 12
  start-page: 1101
  year: 2020
  ident: 39_CR6
  publication-title: Pharmaceutics
  doi: 10.3390/pharmaceutics12111101
– volume: 58
  start-page: 101818
  year: 2020
  ident: 39_CR8
  publication-title: J. Drug Deliv. Sci. Technol.
  doi: 10.1016/j.jddst.2020.101818
– volume: 34
  start-page: 2223
  year: 2017
  ident: 39_CR83
  publication-title: Pharm. Res.
  doi: 10.1007/s11095-017-2223-2
– volume: 201
  start-page: 109485
  year: 2021
  ident: 39_CR45
  publication-title: Mater. Des.
  doi: 10.1016/j.matdes.2021.109485
– volume: 14
  start-page: 409
  year: 2022
  ident: 39_CR89
  publication-title: Pharmaceutics
  doi: 10.3390/pharmaceutics14020409
– volume: 338
  start-page: 394
  year: 2021
  ident: 39_CR25
  publication-title: J. Control. Release
  doi: 10.1016/j.jconrel.2021.08.054
– volume: 13
  start-page: 974
  year: 2022
  ident: 39_CR97
  publication-title: J. Pharm. Negat. Results
– volume: 149
  start-page: 198
  year: 2022
  ident: 39_CR101
  publication-title: Acta. Biomater.
  doi: 10.1016/j.actbio.2022.06.046
– volume: 13
  start-page: 4022
  year: 2012
  ident: 39_CR68
  publication-title: Biomacromolecules
  doi: 10.1021/bm301293d
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SubjectTerms Anti-inflammatory agents
Barrier layers
biodegradability
Biodegradation
Biotechnology
Chemistry
Chemistry and Materials Science
digestive tract
Dissolution
Drug delivery
Drug delivery systems
Drugs
Gastrointestinal diseases
Gastrointestinal system
Gastrointestinal tract
Industrial and Production Engineering
Inflammation
Irritation
mucosa
Nanoparticles
Needles
permeability
Polymers
Production methods
Review Paper
Side effects
Skin
skin irritation
Stratum corneum
생물공학
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