Production of Tagatose by Whole-cell Bioconversion from Fructose Using Corynebacterium glutamicum

• Published in: Biotechnology and bioprocess engineering Vol. 28; no. 3; pp. 419 - 427
• Main Authors: Jeon, Eun Jung, Lee, Young-Mi, Choi, Eun Jung, Kim, Seong-Bo, Jeong, Ki Jun
• Format: Journal Article
• Language: English
• Published: Seoul The Korean Society for Biotechnology and Bioengineering 01.06.2023; Springer Nature B.V; 한국생물공학회
• Subjects: Antisense RNA; Biocatalysts; Bioconversion; Bioengineering; Biotechnology; biotransformation; Calories; Chemistry; Chemistry and Materials Science; Cloning; Copy number; Corynebacterium glutamicum; E coli; Enzymes; Epimerase; Flow cytometry; Fructose; Fruits; Gene expression; Genetic engineering; High-throughput screening; Industrial and Production Engineering; Kosmotoga; Lactose; Optimization; Plasmids; Research centers; Research Paper; Sucrose; Sweetness; Synthetic biology; tagatose; Thermotoga neapolitana; 생물공학; tagatose; fructose; high copy plasmids; whole-cell biocatalyst

s Tagatose is a rarely occurring sugar found in food and sweet fruits. It is a potential sweetener with low calories but a sweetness similar to that of sucrose. In this study, we developed a whole-cell biocatalyst using Corynebacterium glutamicum for direct bioconversion of fructose to tagatose. Fir...