Microbial transglutaminase alters the immunogenic potential and cross-reactivity of horse and cow milk proteins
Horse milk is a valuable raw material and a very attractive alternative for scientific research to address the issue of cow milk (CM) allergy due to its protein profile. A decrease in immunoreactive properties can be achieved by thermal, enzymatic, and hydrolytic processing. Therefore, the aim of th...
Saved in:
Published in | Journal of dairy science Vol. 103; no. 3; pp. 2153 - 2166 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
01.03.2020
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Horse milk is a valuable raw material and a very attractive alternative for scientific research to address the issue of cow milk (CM) allergy due to its protein profile. A decrease in immunoreactive properties can be achieved by thermal, enzymatic, and hydrolytic processing. Therefore, the aim of this study was to explore the possibility of reducing the immunoreactivity of horse milk proteins by microbial transglutaminase (TG) polymerization. To determine how TG linking alters immunoreactivity under simulated digestion of the examined milk, analyses were performed before, during, and after digestion. The dose-dependent (1, 10, and 100 U) effects of microbial TG on horse and cow milk were analyzed. A consecutive 3-stage digestion was simulated with salivary, gastric, and intestinal fluids. The effects of digestion were analyzed by SDS-PAGE, particle size analysis, and size-exclusion chromatography. Immunoreactivity was assessed using competitive ELISA (β-lactoglobulin and α-casein) and immunodot (sera from 7 patients aged 3 to 13 years who are allergic to CM proteins). Horse milk contained almost half of the amount of total proteins in CM. The dose 1 U/g of total milk protein changed the immunoreactivity of both cow and horse milk. With increasing TG doses, α-casein immunoreactivity increased, and β-lactoglobulin decreased. After total digestion, horse milk was characterized by 2.4-fold lower average IgE and 4.8-fold lower IgG reactivity than CM. We found that TG alters the IgE and IgG reactivity of CM after in vitro digestion. Horse milk was less reactive to IgE and IgG than was CM, with animal and patient sera. The effect of TG on immunoreactivity depends on enzyme quantity and milk protein type. The diet based on modified horse milk proteins could be an alternative for some patients with CM protein allergy; however, confirmation through clinical trials is needed. |
---|---|
AbstractList | Horse milk is a valuable raw material and a very attractive alternative for scientific research to address the issue of cow milk (CM) allergy due to its protein profile. A decrease in immunoreactive properties can be achieved by thermal, enzymatic, and hydrolytic processing. Therefore, the aim of this study was to explore the possibility of reducing the immunoreactivity of horse milk proteins by microbial transglutaminase (TG) polymerization. To determine how TG linking alters immunoreactivity under simulated digestion of the examined milk, analyses were performed before, during, and after digestion. The dose-dependent (1, 10, and 100 U) effects of microbial TG on horse and cow milk were analyzed. A consecutive 3-stage digestion was simulated with salivary, gastric, and intestinal fluids. The effects of digestion were analyzed by SDS-PAGE, particle size analysis, and size-exclusion chromatography. Immunoreactivity was assessed using competitive ELISA (β-lactoglobulin and α-casein) and immunodot (sera from 7 patients aged 3 to 13 years who are allergic to CM proteins). Horse milk contained almost half of the amount of total proteins in CM. The dose 1 U/g of total milk protein changed the immunoreactivity of both cow and horse milk. With increasing TG doses, α-casein immunoreactivity increased, and β-lactoglobulin decreased. After total digestion, horse milk was characterized by 2.4-fold lower average IgE and 4.8-fold lower IgG reactivity than CM. We found that TG alters the IgE and IgG reactivity of CM after in vitro digestion. Horse milk was less reactive to IgE and IgG than was CM, with animal and patient sera. The effect of TG on immunoreactivity depends on enzyme quantity and milk protein type. The diet based on modified horse milk proteins could be an alternative for some patients with CM protein allergy; however, confirmation through clinical trials is needed. |
Author | Rigby, N. Fotschki, J. Fotschki, B. Kalicki, B. Mackie, A. Wróblewska, B. |
Author_xml | – sequence: 1 givenname: J. orcidid: 0000-0002-0116-0909 surname: Fotschki fullname: Fotschki, J. email: j.fotschki@pan.olsztyn.pl organization: Department of Immunology and Food Microbiology, Division of Food Science, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-748 Olsztyn, Poland – sequence: 2 givenname: B. orcidid: 0000-0002-7383-7819 surname: Wróblewska fullname: Wróblewska, B. organization: Department of Immunology and Food Microbiology, Division of Food Science, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-748 Olsztyn, Poland – sequence: 3 givenname: B. orcidid: 0000-0002-9727-7481 surname: Fotschki fullname: Fotschki, B. organization: Department of Biological Function of Food, Division of Food Science, Institute of Animal Reproduction and Food Research, Polish Academy of Sciences, 10-748 Olsztyn, Poland – sequence: 4 givenname: B. surname: Kalicki fullname: Kalicki, B. organization: Department of Pediatrics, Nephrology and Allergology, Military Institute of Medicine, 04-141 Warsaw, Poland – sequence: 5 givenname: N. surname: Rigby fullname: Rigby, N. organization: Institute of Food Research, Norwich NR4 7UA, United Kingdom – sequence: 6 givenname: A. surname: Mackie fullname: Mackie, A. organization: Institute of Food Research, Norwich NR4 7UA, United Kingdom |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31928755$$D View this record in MEDLINE/PubMed |
BookMark | eNp1kDtPwzAURi0EgrawMiKPLCl-NA-PqOIlgVhgtlznpjUkdrGdov57nLawMVlX93yfdc8YHVtnAaFLSqacFtXNRx2mjFCR0ZIVsyM0ojnLM05FdYxGhDCWEU7YGRqH8JFGykh-is7SnlVlno-QezHau4VRLY5e2bBs-6g6Y1UArNoIPuC4Amy6rrduCdZovHYRbBwSytY4pUPIPCgdzcbELXYNXjk_xIet-8adaT_x2qeUseEcnTSqDXBxeCfo_f7ubf6YPb8-PM1vnzPNq1nMgPKccygboUqua8Z1ISjXMGOQl5RpIKxpFIgZJ4IVvKC6AMoWVFecCZEDn6DrfW_6-KuHEGVngoa2VRZcHyTjvCIlqQRJ6HSP7k7x0Mi1N53yW0mJHCTLJFkOkuVOcgpcHbr7RQf1H_5rNQHVHoB04caAl0EbsBpq40FHWTvzX_cPo92OYg |
CitedBy_id | crossref_primary_10_1016_j_foodchem_2022_134777 crossref_primary_10_1016_j_lwt_2023_115417 crossref_primary_10_3390_foods10010163 crossref_primary_10_1016_j_lwt_2021_111178 crossref_primary_10_1016_j_foodres_2020_109780 crossref_primary_10_21323_2618_9771_2021_4_4_294_307 crossref_primary_10_3390_cimb45050260 crossref_primary_10_1016_j_fochx_2022_100482 crossref_primary_10_3390_ijms241512402 crossref_primary_10_3390_nu14214584 crossref_primary_10_1016_j_idairyj_2023_105808 |
Cites_doi | 10.1016/j.foodhyd.2011.06.003 10.1046/j.1365-2222.2003.01795.x 10.1016/j.jaci.2008.05.043 10.1111/j.1749-6632.2002.tb04136.x 10.1016/S1081-1206(10)62120-5 10.1021/jf402824u 10.1002/mnfr.200800236 10.1007/s00217-012-1802-z 10.1016/j.yrtph.2009.08.010 10.1017/S0022029914000612 10.1039/C3FO60702J 10.1021/jf802596g 10.1016/j.foodres.2016.02.016 10.1177/1082013209346369 10.1016/j.foodhyd.2010.07.010 10.1111/j.1365-2621.2003.tb08249.x 10.1007/s12223-013-0287-x 10.1038/227680a0 10.1067/mai.2000.106377 10.1016/j.idairyj.2010.01.004 10.1016/j.idairyj.2010.02.007 10.3945/jn.114.204339 10.1016/j.foodchem.2009.10.053 10.1002/mnfr.200400011 10.1111/ijfs.12054 10.1016/j.foodhyd.2009.06.023 10.1007/s11274-010-0446-z 10.1016/j.tifs.2016.01.001 10.1097/ACI.0b013e3282ffb123 10.6061/clinics/2012(10)09 10.1067/mai.2001.114708 10.1016/0003-2697(76)90527-3 10.1002/mnfr.200400014 10.1016/j.foodres.2009.04.022 10.1016/j.ymeth.2013.08.005 10.1002/pmic.200300765 10.1186/1476-7961-7-1 10.1016/j.idairyj.2006.01.007 10.1002/mnfr.200800187 10.1016/j.idairyj.2012.02.007 10.1016/j.foodres.2015.04.001 10.1016/j.mimet.2016.05.007 10.1002/mnfr.200900184 10.3168/jds.2016-11499 10.1093/toxsci/55.2.235 10.1080/10408398.2017.1363156 |
ContentType | Journal Article |
Copyright | 2020 American Dairy Science Association Copyright © 2020 American Dairy Science Association. Published by Elsevier Inc. All rights reserved. |
Copyright_xml | – notice: 2020 American Dairy Science Association – notice: Copyright © 2020 American Dairy Science Association. Published by Elsevier Inc. All rights reserved. |
DBID | NPM AAYXX CITATION 7X8 |
DOI | 10.3168/jds.2019-17264 |
DatabaseName | PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | PubMed CrossRef MEDLINE - Academic |
DatabaseTitleList | PubMed |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Agriculture |
EISSN | 1525-3198 |
EndPage | 2166 |
ExternalDocumentID | 10_3168_jds_2019_17264 31928755 S0022030220300072 |
Genre | Journal Article |
GroupedDBID | --- --K -~X .GJ 0R~ 0SF 186 18M 1B1 29K 2WC 36B 3V. 4.4 457 4G. 53G 5GY 5VS 7-5 7X2 7X7 7XC 88E 8FE 8FG 8FH 8FI 8FJ 8FW 8R4 8R5 8VB AABVA AAEDT AAEDW AAFTH AAIAV AALRI AAQFI AAQXK AAWRB AAXUO ABCQX ABJCF ABJNI ABUWG ABVKL ACGFO ACGFS ACIWK ADBBV ADMUD ADPAM AEGXH AENEX AESVU AFKRA AFKWA AFRAH AFTJW AGZHU AHMBA AI. AIAGR AITUG AKVCP ALMA_UNASSIGNED_HOLDINGS ALXNB AMRAJ ASPBG ATCPS AVWKF AZFZN BELOY BENPR BGLVJ BHPHI BPHCQ BVXVI C1A CCPQU CS3 D-I DU5 E3Z EBS EBU EDH EJD EMB F5P FDB FEDTE FGOYB FYUFA GBLVA GROUPED_DOAJ GX1 HCIFZ HMCUK HVGLF HZ~ K1G L6V L7B M0K M1P M41 M7S N9A NCXOZ NHB O9- OK1 P2P PATMY PQQKQ PROAC PSQYO PTHSS PYCSY Q2X QII QWB R2- ROL RWL S0X SEL SES SSZ SV3 TAE TDS TWZ U5U UHB UKHRP VH1 WOQ XH2 XOL ZGI ZL0 ZXP ~KM AAHBH ADMHG ADVLN AFJKZ AKRWK ALIPV NPM AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c384t-e13533e7f9a73cd23c6913ce42e5712ce02ffae9430926361c6e12b1c832995e3 |
IEDL.DBID | ABVKL |
ISSN | 0022-0302 |
IngestDate | Fri Aug 16 01:51:26 EDT 2024 Thu Sep 26 19:45:35 EDT 2024 Wed Oct 16 00:46:43 EDT 2024 Fri Feb 23 02:48:55 EST 2024 |
IsDoiOpenAccess | false |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 3 |
Keywords | microbial transglutaminase horse milk cow milk protein allergy simulated gastrointestinal digestion |
Language | English |
License | Copyright © 2020 American Dairy Science Association. Published by Elsevier Inc. All rights reserved. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c384t-e13533e7f9a73cd23c6913ce42e5712ce02ffae9430926361c6e12b1c832995e3 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0002-7383-7819 0000-0002-9727-7481 0000-0002-0116-0909 |
OpenAccessLink | http://www.journalofdairyscience.org/article/S0022030220300072/pdf |
PMID | 31928755 |
PQID | 2338070890 |
PQPubID | 23479 |
PageCount | 14 |
ParticipantIDs | proquest_miscellaneous_2338070890 crossref_primary_10_3168_jds_2019_17264 pubmed_primary_31928755 elsevier_sciencedirect_doi_10_3168_jds_2019_17264 |
PublicationCentury | 2000 |
PublicationDate | March 2020 2020-Mar 2020-03-00 20200301 |
PublicationDateYYYYMMDD | 2020-03-01 |
PublicationDate_xml | – month: 03 year: 2020 text: March 2020 |
PublicationDecade | 2020 |
PublicationPlace | United States |
PublicationPlace_xml | – name: United States |
PublicationTitle | Journal of dairy science |
PublicationTitleAlternate | J Dairy Sci |
PublicationYear | 2020 |
Publisher | Elsevier Inc |
Publisher_xml | – name: Elsevier Inc |
References | Kieliszek, Misiewicz (bib22) 2014; 59 Fotschki, Szyc, Laparra, Markiewicz, Wróblewska (bib11) 2016; 99 Businco, Giampietro, Lucenti, Lucaroni, Pini, Di Felice, Iacovacci, Curadi, Orlandi (bib3) 2000; 105 Wróblewska, Kołakowski, Pawlikowska, Troszyńska, Kaliszewska (bib49) 2009; 23 Fotschki, Szyc, Wróblewska (bib10) 2015; 82 Olivier, Lima, Pinto, Santos, Silva, Lorena, Villas-Boas, Netto, Zollner (bib34) 2012; 67 Golkar, Milani, Vasiljevic (bib14) 2019; 59 Teuber (bib43) 2002; 964 Wróblewska, Markiewicz, Szyc, Dietrich, Szymkiewicz, Fotschki (bib50) 2016; 83 de Souza, Venzke, Flôres, Ayub (bib7) 2009; 15 Fiocchi, Brozek, Schünemann, Bahna, von Berg, Beyer, Bozzola, Bradsher, Compalati, Ebisawa, Guzman, Li, Heine, Keith, Lack, Landi, Martelli, Rance, Sampson, Stein, Terracciano, Vieths (bib9) 2010; 21 de Jong, Wijngaards, Koppelman (bib6) 2003; 68 Nowak-Wegrzyn, Bloom, Sicherer, Shreffler, Noone, Wanich, Sampson (bib33) 2008; 122 Markiewicz, Szymkiewicz, Szyc, Wróblewska (bib26) 2016; 126 Laemmli (bib23) 1970; 227 Wróblewska, Kaliszewska-Suchodoła, Kołakowski, Troszyńska (bib48) 2013; 48 Schnell, Herman (bib41) 2009; 7 Uniacke-Lowe, Huppertz, Fox (bib44) 2010; 20 Bradford (bib2) 1976; 72 Havenaar, de Jong, Koenen, van Bilsen, Janssen, Labij, Westerbeek (bib16) 2013; 61 Høst (bib19) 2002; 89 Danków, Pikul, Osten-Sacken, Teichert (bib5) 2012; 6 Villas-Boas, Fernandes, Zollner, Netto (bib45) 2012; 25 El-Zeini (bib8) 2006; 15 Giosafatto, Rigby, Wellner, Ridout, Husband, Mackie (bib13) 2012; 26 Mills, Sancho, Rigby, Jenkins, Mackie (bib29) 2009; 53 Sabadin, Villas-Boas, de Lima Zollner, Netto (bib39) 2012; 235 Miranda, Mahé, Leroux, Martin (bib31) 2004; 4 Bönisch, Lauber, Kulozik (bib1) 2007; 17 Rahaman, Vasiljevic, Ramchandran (bib38) 2016; 49 Hussein, Hoad, Wright, Singh, Stephenson, Cox, Placidi, Pritchard, Costigan, Ribeiro, Ciampi, Nandi, Hedges, Sanderson, Peters, Rayment, Spiller, Gowland, Marciani (bib21) 2015; 145 Pedersen, Hansen, Sten, Seguro, Ohtsuka, Morita, Bindslev-Jensen, Poulsen (bib36) 2004; 48 Potočnik, Gantner, Kuterovac, Angela (bib37) 2011; 61 Stanic, Monogioudi, Ercili, Radosavljevic, Atanaskovic-Markovic, Vuckovic, Raija, Mattinen, Buchert, Cirkovic Velickovic (bib42) 2010; 54 Ménard, Ahmad, Rousseau, Briard-Bion, Gaucheron, Lopez (bib27) 2010; 120 Macierzanka, Bordron, Rigby, Mills, Lille, Poutanen, Mackie (bib24) 2011; 25 Mills, Mackie (bib28) 2008; 8 Fotschki, Szyc, Laparra, Wróblewska (bib12) 2015; 72 Hochwallner, Schulmeister, Swoboda, Spitzauer, Valenta (bib18) 2014; 66 Huby (bib20) 2000; 55 Villas-Boas, Vieira, Trevizan, de Lima Zollner, Netto (bib46) 2010; 20 Sampson (bib40) 2001; 107 Natale, Bisson, Monti, Peltran, Garoffo, Valentini, Fabris, Bertino, Coscia, Conti (bib32) 2004; 48 Mandalari, Adel-Patient, Barkholt, Baro, Bennett, Bublin, Gaier, Graser, Ladics, Mierzejewska, Vassilopoulou, Vissers, Zuidmeer, Rigby, Salt, Defernez, Mulholland, Mackie, Wickham, Mills (bib25) 2009; 55 Paschke (bib35) 2009; 53 Hiller, Lorenzen (bib17) 2009; 42 Wróblewska, Kaliszewska, Kołakowski, Pawlikowska, Troszyńska (bib47) 2011; 27 Grimshaw, King, Nordlee, Hefle, Warner, Hourihane (bib15) 2003; 33 Minekus, Alminger, Alvito, Ballance, Bohn, Bourlieu, Carrière, Boutrou, Corredig, Dupont, Dufour, Egger, Golding, Karakaya, Kirkhus, Le Feunteun, Lesmes, Macierzanka, Mackie, Marze, McClements, Ménard, Recio, Santos, Singh, Vegarud, Wickham, Weitschies, Brodkorb (bib30) 2014; 5 Cabrera-Chávez, Rouzaud-Sández, Sotelo-Cruz, Calderón de la Barca (bib4) 2009; 57 Minekus (10.3168/jds.2019-17264_bib30) 2014; 5 Giosafatto (10.3168/jds.2019-17264_bib13) 2012; 26 Fotschki (10.3168/jds.2019-17264_bib10) 2015; 82 Havenaar (10.3168/jds.2019-17264_bib16) 2013; 61 Schnell (10.3168/jds.2019-17264_bib41) 2009; 7 Hussein (10.3168/jds.2019-17264_bib21) 2015; 145 Laemmli (10.3168/jds.2019-17264_bib23) 1970; 227 Mills (10.3168/jds.2019-17264_bib28) 2008; 8 Fotschki (10.3168/jds.2019-17264_bib11) 2016; 99 Businco (10.3168/jds.2019-17264_bib3) 2000; 105 Stanic (10.3168/jds.2019-17264_bib42) 2010; 54 Grimshaw (10.3168/jds.2019-17264_bib15) 2003; 33 Potočnik (10.3168/jds.2019-17264_bib37) 2011; 61 Wróblewska (10.3168/jds.2019-17264_bib49) 2009; 23 de Souza (10.3168/jds.2019-17264_bib7) 2009; 15 Fotschki (10.3168/jds.2019-17264_bib12) 2015; 72 Paschke (10.3168/jds.2019-17264_bib35) 2009; 53 Olivier (10.3168/jds.2019-17264_bib34) 2012; 67 Sampson (10.3168/jds.2019-17264_bib40) 2001; 107 Bradford (10.3168/jds.2019-17264_bib2) 1976; 72 Ménard (10.3168/jds.2019-17264_bib27) 2010; 120 Bönisch (10.3168/jds.2019-17264_bib1) 2007; 17 Danków (10.3168/jds.2019-17264_bib5) 2012; 6 Wróblewska (10.3168/jds.2019-17264_bib50) 2016; 83 de Jong (10.3168/jds.2019-17264_bib6) 2003; 68 Fiocchi (10.3168/jds.2019-17264_bib9) 2010; 21 Natale (10.3168/jds.2019-17264_bib32) 2004; 48 Huby (10.3168/jds.2019-17264_bib20) 2000; 55 Macierzanka (10.3168/jds.2019-17264_bib24) 2011; 25 Mills (10.3168/jds.2019-17264_bib29) 2009; 53 Pedersen (10.3168/jds.2019-17264_bib36) 2004; 48 Markiewicz (10.3168/jds.2019-17264_bib26) 2016; 126 Cabrera-Chávez (10.3168/jds.2019-17264_bib4) 2009; 57 Mandalari (10.3168/jds.2019-17264_bib25) 2009; 55 Villas-Boas (10.3168/jds.2019-17264_bib46) 2010; 20 Wróblewska (10.3168/jds.2019-17264_bib48) 2013; 48 Wróblewska (10.3168/jds.2019-17264_bib47) 2011; 27 Sabadin (10.3168/jds.2019-17264_bib39) 2012; 235 Teuber (10.3168/jds.2019-17264_bib43) 2002; 964 Rahaman (10.3168/jds.2019-17264_bib38) 2016; 49 Høst (10.3168/jds.2019-17264_bib19) 2002; 89 Miranda (10.3168/jds.2019-17264_bib31) 2004; 4 El-Zeini (10.3168/jds.2019-17264_bib8) 2006; 15 Golkar (10.3168/jds.2019-17264_bib14) 2019; 59 Hochwallner (10.3168/jds.2019-17264_bib18) 2014; 66 Uniacke-Lowe (10.3168/jds.2019-17264_bib44) 2010; 20 Villas-Boas (10.3168/jds.2019-17264_bib45) 2012; 25 Kieliszek (10.3168/jds.2019-17264_bib22) 2014; 59 Nowak-Wegrzyn (10.3168/jds.2019-17264_bib33) 2008; 122 Hiller (10.3168/jds.2019-17264_bib17) 2009; 42 |
References_xml | – volume: 66 start-page: 22 year: 2014 end-page: 33 ident: bib18 article-title: Cow's milk allergy: From allergens to new forms of diagnosis, therapy and prevention publication-title: Methods contributor: fullname: Valenta – volume: 20 start-page: 386 year: 2010 end-page: 392 ident: bib46 article-title: The effect of transglutaminase-induced polymerization in the presence of cysteine on β-lactoglobulin antigenicity publication-title: Int. Dairy J. contributor: fullname: Netto – volume: 6 start-page: 16 year: 2012 ident: bib5 article-title: Charakterystyka i właściwości prozdrowotne mleka klaczy (Characteristics and salubrious properties of mare milk) publication-title: Nauka Przyr. Tech. contributor: fullname: Teichert – volume: 82 start-page: 78 year: 2015 end-page: 85 ident: bib10 article-title: Immunoreactivity of lactic acid-treated mare's milk after simulated digestion publication-title: J. Dairy Res. contributor: fullname: Wróblewska – volume: 235 start-page: 801 year: 2012 end-page: 809 ident: bib39 article-title: Effect of combined treatment of hydrolysis and polymerization with transglutaminase on β-lactoglobulin antigenicity publication-title: Eur. Food Res. Technol. contributor: fullname: Netto – volume: 26 start-page: 261 year: 2012 end-page: 267 ident: bib13 article-title: Microbial transglutaminase-mediated modification of ovalbumin publication-title: Food Hydrocoll. contributor: fullname: Mackie – volume: 15 start-page: 147 year: 2006 end-page: 153 ident: bib8 article-title: Microstructure, rheological and geometrical properties of fat globules of milk from different animal species publication-title: Pol. J. Food Nutr. Sci. contributor: fullname: El-Zeini – volume: 107 start-page: 891 year: 2001 end-page: 896 ident: bib40 article-title: Utility of food-specific IgE concentrations in predicting symptomatic food allergy publication-title: J. Allergy Clin. Immunol. contributor: fullname: Sampson – volume: 67 start-page: 1171 year: 2012 end-page: 1179 ident: bib34 article-title: In search of a tolerance-induction strategy for cow's milk allergies: Significant reduction of beta-lactoglobulin allergenicity via transglutaminase/cysteine polymerization: Allergoid generation by polymerization publication-title: Clinics (São Paulo) contributor: fullname: Zollner – volume: 4 start-page: 2496 year: 2004 end-page: 2509 ident: bib31 article-title: Proteomic tools to characterize the protein fraction of publication-title: Proteomics contributor: fullname: Martin – volume: 7 start-page: 1 year: 2009 ident: bib41 article-title: Should digestion assays be used to estimate persistence of potential allergens in tests for safety of novel food proteins? publication-title: Clin. Mol. Allergy contributor: fullname: Herman – volume: 33 start-page: 1581 year: 2003 end-page: 1585 ident: bib15 article-title: Presentation of allergen in different food preparations affects the nature of the allergic reaction—A case series publication-title: Clin. Exp. Allergy contributor: fullname: Hourihane – volume: 27 start-page: 215 year: 2011 end-page: 227 ident: bib47 article-title: Impact of transglutaminase reaction on the immunoreactive and sensory quality of yoghurt starter publication-title: World J. Microbiol. Biotechnol. contributor: fullname: Troszyńska – volume: 5 start-page: 1113 year: 2014 end-page: 1124 ident: bib30 article-title: A standardised static in vitro digestion method suitable for food—An international consensus publication-title: Food Funct. contributor: fullname: Brodkorb – volume: 964 start-page: 111 year: 2002 end-page: 116 ident: bib43 article-title: Hypothesis: The protein body effect and other aspects of food matrix effects publication-title: Ann. N. Y. Acad. Sci. contributor: fullname: Teuber – volume: 48 start-page: 434 year: 2004 end-page: 440 ident: bib36 article-title: Evaluation of the potential allergenicity of the enzyme microbial transglutaminase using the 2001 FAO/WHO decision tree publication-title: Mol. Nutr. Food Res. contributor: fullname: Poulsen – volume: 15 start-page: 337 year: 2009 end-page: 344 ident: bib7 article-title: Nutritional effects of mechanically deboned chicken meat and soybean proteins cross-linking by microbial transglutaminase publication-title: Food Sci. Technol. Int. contributor: fullname: Ayub – volume: 42 start-page: 899 year: 2009 end-page: 908 ident: bib17 article-title: Functional properties of milk proteins as affected by enzymatic oligomerisation publication-title: Food Res. Int. contributor: fullname: Lorenzen – volume: 17 start-page: 3 year: 2007 end-page: 11 ident: bib1 article-title: Improvement of enzymatic cross-linking of casein micelles with transglutaminase by glutathione addition publication-title: Int. Dairy J. contributor: fullname: Kulozik – volume: 21 start-page: 1 year: 2010 end-page: 125 ident: bib9 article-title: World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guidelines publication-title: Pediatr. Allergy Immunol. contributor: fullname: Vieths – volume: 61 start-page: 7636 year: 2013 end-page: 7644 ident: bib16 article-title: Digestibility of transglutaminase cross-linked caseinate versus native caseinate in an in vitro multicompartmental model simulating young child and adult gastrointestinal conditions publication-title: J. Agric. Food Chem. contributor: fullname: Westerbeek – volume: 120 start-page: 544 year: 2010 end-page: 551 ident: bib27 article-title: Buffalo vs. cow milk fat globules: Size distribution, zeta-potential, compositions in total fatty acids and in polar lipids from the milk fat globule membrane publication-title: Food Chem. contributor: fullname: Lopez – volume: 8 start-page: 249 year: 2008 end-page: 253 ident: bib28 article-title: The impact of processing on allergenicity of food publication-title: Curr. Opin. Allergy Clin. Immunol. contributor: fullname: Mackie – volume: 61 start-page: 107 year: 2011 end-page: 113 ident: bib37 article-title: Mare's milk: Composition and protein fraction in comparison with different milk species publication-title: Mljekarstvo contributor: fullname: Angela – volume: 48 start-page: 363 year: 2004 end-page: 369 ident: bib32 article-title: Cow's milk allergens identification by two-dimensional immunoblotting and mass spectrometry publication-title: Mol. Nutr. Food Res. contributor: fullname: Conti – volume: 55 start-page: 372 year: 2009 end-page: 381 ident: bib25 article-title: In vitro digestibility of β-casein and β-lactoglobulin under simulated human gastric and duodenal conditions: A multi-laboratory evaluation publication-title: Regul. Toxicol. Pharmacol. contributor: fullname: Mills – volume: 59 start-page: 159 year: 2019 end-page: 172 ident: bib14 article-title: Altering allergenicity of cow's milk by food processing for applications in infant formula publication-title: Crit. Rev. Food Sci. Nutr. contributor: fullname: Vasiljevic – volume: 53 start-page: 959 year: 2009 end-page: 962 ident: bib35 article-title: Aspects of food processing and its effect on allergen structure publication-title: Mol. Nutr. Food Res. contributor: fullname: Paschke – volume: 25 start-page: 843 year: 2011 end-page: 850 ident: bib24 article-title: Transglutaminase cross-linking kinetics of sodium caseinate is changed after emulsification publication-title: Food Hydrocoll. contributor: fullname: Mackie – volume: 145 start-page: 1170 year: 2015 end-page: 1177 ident: bib21 article-title: Fat emulsion intragastric stability and droplet size modulate gastrointestinal responses and subsequent food intake in young adults publication-title: J. Nutr. contributor: fullname: Marciani – volume: 25 start-page: 123 year: 2012 end-page: 131 ident: bib45 article-title: Effect of polymerization with transglutaminase on in vitro digestion and antigenicity of β-lactoglobulin publication-title: Int. Dairy J. contributor: fullname: Netto – volume: 59 start-page: 241 year: 2014 end-page: 250 ident: bib22 article-title: Microbial transglutaminase and its application in the food industry. A review publication-title: Folia Microbiol. (Praha) contributor: fullname: Misiewicz – volume: 89 start-page: 33 year: 2002 end-page: 37 ident: bib19 article-title: Frequency of cow's milk allergy in childhood publication-title: Ann. Allergy Asthma Immunol. contributor: fullname: Høst – volume: 20 start-page: 609 year: 2010 end-page: 629 ident: bib44 article-title: Equine milk proteins: Chemistry, structure and nutritional significance publication-title: Int. Dairy J. contributor: fullname: Fox – volume: 227 start-page: 680 year: 1970 end-page: 685 ident: bib23 article-title: Cleavage of structural proteins during the assembly of the head of bacteriophage T4 publication-title: Nature contributor: fullname: Laemmli – volume: 99 start-page: 9395 year: 2016 end-page: 9404 ident: bib11 article-title: Immune-modulating properties of horse milk administered to mice sensitized to cow milk publication-title: J. Dairy Sci. contributor: fullname: Wróblewska – volume: 105 start-page: 1031 year: 2000 end-page: 1034 ident: bib3 article-title: Allergenicity of mare's milk in children with cow's milk allergy publication-title: J. Allergy Clin. Immunol. contributor: fullname: Orlandi – volume: 68 start-page: 820 year: 2003 end-page: 825 ident: bib6 article-title: Transglutaminase inhibitor from milk publication-title: J. Food Sci. contributor: fullname: Koppelman – volume: 126 start-page: 72 year: 2016 end-page: 75 ident: bib26 article-title: A simultaneous two-colour detection method of human IgG- and IgE-reactive proteins from lactic acid bacteria publication-title: J. Microbiol. Methods contributor: fullname: Wróblewska – volume: 23 start-page: 2434 year: 2009 end-page: 2445 ident: bib49 article-title: Influence of the addition of transglutaminase on the immunoreactivity of milk proteins and sensory quality of kefir publication-title: Food Hydrocoll. contributor: fullname: Kaliszewska – volume: 72 start-page: 248 year: 1976 end-page: 254 ident: bib2 article-title: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding publication-title: Anal. Biochem. contributor: fullname: Bradford – volume: 55 start-page: 235 year: 2000 end-page: 246 ident: bib20 article-title: Why are some proteins allergens? publication-title: Toxicol. Sci. contributor: fullname: Huby – volume: 48 start-page: 1007 year: 2013 end-page: 1017 ident: bib48 article-title: The effect of microbial transglutaminase on the immunoreactive and sensory properties of fermented milk beverages publication-title: Int. J. Food Sci. Technol. contributor: fullname: Troszyńska – volume: 83 start-page: 95 year: 2016 end-page: 101 ident: bib50 article-title: LcY decreases milk protein immunoreactivity of fermented buttermilk but also contains IgE-reactive proteins publication-title: Food Res. Int. contributor: fullname: Fotschki – volume: 57 start-page: 3754 year: 2009 end-page: 3759 ident: bib4 article-title: Bovine milk caseins and transglutaminase-treated cereal prolamins are differentially recognized by IgA of celiac disease patients according to their age publication-title: J. Agric. Food Chem. contributor: fullname: Calderón de la Barca – volume: 53 start-page: 963 year: 2009 end-page: 969 ident: bib29 article-title: Impact of food processing on the structural and allergenic properties of food allergens publication-title: Mol. Nutr. Food Res. contributor: fullname: Mackie – volume: 49 start-page: 24 year: 2016 end-page: 34 ident: bib38 article-title: Effect of processing on conformational changes of food proteins related to allergenicity publication-title: Trends Food Sci. Technol. contributor: fullname: Ramchandran – volume: 54 start-page: 1273 year: 2010 end-page: 1284 ident: bib42 article-title: Digestibility and allergenicity assessment of enzymatically crosslinked β-casein publication-title: Mol. Nutr. Food Res. contributor: fullname: Cirkovic Velickovic – volume: 72 start-page: 184 year: 2015 end-page: 190 ident: bib12 article-title: Mare's and cow's milk: Promote similar metabolic effects and expression of innate markers in Caco-2 cells? publication-title: Food Res. Int. contributor: fullname: Wróblewska – volume: 122 start-page: 342 year: 2008 end-page: 347 ident: bib33 article-title: Tolerance to extensively heated milk in children with cow's milk allergy publication-title: J. Allergy Clin. Immunol. contributor: fullname: Sampson – volume: 26 start-page: 261 year: 2012 ident: 10.3168/jds.2019-17264_bib13 article-title: Microbial transglutaminase-mediated modification of ovalbumin publication-title: Food Hydrocoll. doi: 10.1016/j.foodhyd.2011.06.003 contributor: fullname: Giosafatto – volume: 33 start-page: 1581 year: 2003 ident: 10.3168/jds.2019-17264_bib15 article-title: Presentation of allergen in different food preparations affects the nature of the allergic reaction—A case series publication-title: Clin. Exp. Allergy doi: 10.1046/j.1365-2222.2003.01795.x contributor: fullname: Grimshaw – volume: 15 start-page: 147 year: 2006 ident: 10.3168/jds.2019-17264_bib8 article-title: Microstructure, rheological and geometrical properties of fat globules of milk from different animal species publication-title: Pol. J. Food Nutr. Sci. contributor: fullname: El-Zeini – volume: 122 start-page: 342 year: 2008 ident: 10.3168/jds.2019-17264_bib33 article-title: Tolerance to extensively heated milk in children with cow's milk allergy publication-title: J. Allergy Clin. Immunol. doi: 10.1016/j.jaci.2008.05.043 contributor: fullname: Nowak-Wegrzyn – volume: 964 start-page: 111 year: 2002 ident: 10.3168/jds.2019-17264_bib43 article-title: Hypothesis: The protein body effect and other aspects of food matrix effects publication-title: Ann. N. Y. Acad. Sci. doi: 10.1111/j.1749-6632.2002.tb04136.x contributor: fullname: Teuber – volume: 89 start-page: 33 year: 2002 ident: 10.3168/jds.2019-17264_bib19 article-title: Frequency of cow's milk allergy in childhood publication-title: Ann. Allergy Asthma Immunol. doi: 10.1016/S1081-1206(10)62120-5 contributor: fullname: Høst – volume: 61 start-page: 7636 year: 2013 ident: 10.3168/jds.2019-17264_bib16 article-title: Digestibility of transglutaminase cross-linked caseinate versus native caseinate in an in vitro multicompartmental model simulating young child and adult gastrointestinal conditions publication-title: J. Agric. Food Chem. doi: 10.1021/jf402824u contributor: fullname: Havenaar – volume: 53 start-page: 963 year: 2009 ident: 10.3168/jds.2019-17264_bib29 article-title: Impact of food processing on the structural and allergenic properties of food allergens publication-title: Mol. Nutr. Food Res. doi: 10.1002/mnfr.200800236 contributor: fullname: Mills – volume: 235 start-page: 801 year: 2012 ident: 10.3168/jds.2019-17264_bib39 article-title: Effect of combined treatment of hydrolysis and polymerization with transglutaminase on β-lactoglobulin antigenicity publication-title: Eur. Food Res. Technol. doi: 10.1007/s00217-012-1802-z contributor: fullname: Sabadin – volume: 55 start-page: 372 year: 2009 ident: 10.3168/jds.2019-17264_bib25 article-title: In vitro digestibility of β-casein and β-lactoglobulin under simulated human gastric and duodenal conditions: A multi-laboratory evaluation publication-title: Regul. Toxicol. Pharmacol. doi: 10.1016/j.yrtph.2009.08.010 contributor: fullname: Mandalari – volume: 82 start-page: 78 year: 2015 ident: 10.3168/jds.2019-17264_bib10 article-title: Immunoreactivity of lactic acid-treated mare's milk after simulated digestion publication-title: J. Dairy Res. doi: 10.1017/S0022029914000612 contributor: fullname: Fotschki – volume: 5 start-page: 1113 year: 2014 ident: 10.3168/jds.2019-17264_bib30 article-title: A standardised static in vitro digestion method suitable for food—An international consensus publication-title: Food Funct. doi: 10.1039/C3FO60702J contributor: fullname: Minekus – volume: 57 start-page: 3754 year: 2009 ident: 10.3168/jds.2019-17264_bib4 article-title: Bovine milk caseins and transglutaminase-treated cereal prolamins are differentially recognized by IgA of celiac disease patients according to their age publication-title: J. Agric. Food Chem. doi: 10.1021/jf802596g contributor: fullname: Cabrera-Chávez – volume: 83 start-page: 95 year: 2016 ident: 10.3168/jds.2019-17264_bib50 article-title: Lactobacillus casei LcY decreases milk protein immunoreactivity of fermented buttermilk but also contains IgE-reactive proteins publication-title: Food Res. Int. doi: 10.1016/j.foodres.2016.02.016 contributor: fullname: Wróblewska – volume: 15 start-page: 337 year: 2009 ident: 10.3168/jds.2019-17264_bib7 article-title: Nutritional effects of mechanically deboned chicken meat and soybean proteins cross-linking by microbial transglutaminase publication-title: Food Sci. Technol. Int. doi: 10.1177/1082013209346369 contributor: fullname: de Souza – volume: 25 start-page: 843 year: 2011 ident: 10.3168/jds.2019-17264_bib24 article-title: Transglutaminase cross-linking kinetics of sodium caseinate is changed after emulsification publication-title: Food Hydrocoll. doi: 10.1016/j.foodhyd.2010.07.010 contributor: fullname: Macierzanka – volume: 68 start-page: 820 year: 2003 ident: 10.3168/jds.2019-17264_bib6 article-title: Transglutaminase inhibitor from milk publication-title: J. Food Sci. doi: 10.1111/j.1365-2621.2003.tb08249.x contributor: fullname: de Jong – volume: 59 start-page: 241 year: 2014 ident: 10.3168/jds.2019-17264_bib22 article-title: Microbial transglutaminase and its application in the food industry. A review publication-title: Folia Microbiol. (Praha) doi: 10.1007/s12223-013-0287-x contributor: fullname: Kieliszek – volume: 227 start-page: 680 year: 1970 ident: 10.3168/jds.2019-17264_bib23 article-title: Cleavage of structural proteins during the assembly of the head of bacteriophage T4 publication-title: Nature doi: 10.1038/227680a0 contributor: fullname: Laemmli – volume: 105 start-page: 1031 year: 2000 ident: 10.3168/jds.2019-17264_bib3 article-title: Allergenicity of mare's milk in children with cow's milk allergy publication-title: J. Allergy Clin. Immunol. doi: 10.1067/mai.2000.106377 contributor: fullname: Businco – volume: 20 start-page: 386 year: 2010 ident: 10.3168/jds.2019-17264_bib46 article-title: The effect of transglutaminase-induced polymerization in the presence of cysteine on β-lactoglobulin antigenicity publication-title: Int. Dairy J. doi: 10.1016/j.idairyj.2010.01.004 contributor: fullname: Villas-Boas – volume: 20 start-page: 609 year: 2010 ident: 10.3168/jds.2019-17264_bib44 article-title: Equine milk proteins: Chemistry, structure and nutritional significance publication-title: Int. Dairy J. doi: 10.1016/j.idairyj.2010.02.007 contributor: fullname: Uniacke-Lowe – volume: 145 start-page: 1170 year: 2015 ident: 10.3168/jds.2019-17264_bib21 article-title: Fat emulsion intragastric stability and droplet size modulate gastrointestinal responses and subsequent food intake in young adults publication-title: J. Nutr. doi: 10.3945/jn.114.204339 contributor: fullname: Hussein – volume: 120 start-page: 544 year: 2010 ident: 10.3168/jds.2019-17264_bib27 article-title: Buffalo vs. cow milk fat globules: Size distribution, zeta-potential, compositions in total fatty acids and in polar lipids from the milk fat globule membrane publication-title: Food Chem. doi: 10.1016/j.foodchem.2009.10.053 contributor: fullname: Ménard – volume: 48 start-page: 363 year: 2004 ident: 10.3168/jds.2019-17264_bib32 article-title: Cow's milk allergens identification by two-dimensional immunoblotting and mass spectrometry publication-title: Mol. Nutr. Food Res. doi: 10.1002/mnfr.200400011 contributor: fullname: Natale – volume: 48 start-page: 1007 year: 2013 ident: 10.3168/jds.2019-17264_bib48 article-title: The effect of microbial transglutaminase on the immunoreactive and sensory properties of fermented milk beverages publication-title: Int. J. Food Sci. Technol. doi: 10.1111/ijfs.12054 contributor: fullname: Wróblewska – volume: 23 start-page: 2434 year: 2009 ident: 10.3168/jds.2019-17264_bib49 article-title: Influence of the addition of transglutaminase on the immunoreactivity of milk proteins and sensory quality of kefir publication-title: Food Hydrocoll. doi: 10.1016/j.foodhyd.2009.06.023 contributor: fullname: Wróblewska – volume: 27 start-page: 215 year: 2011 ident: 10.3168/jds.2019-17264_bib47 article-title: Impact of transglutaminase reaction on the immunoreactive and sensory quality of yoghurt starter publication-title: World J. Microbiol. Biotechnol. doi: 10.1007/s11274-010-0446-z contributor: fullname: Wróblewska – volume: 61 start-page: 107 year: 2011 ident: 10.3168/jds.2019-17264_bib37 article-title: Mare's milk: Composition and protein fraction in comparison with different milk species publication-title: Mljekarstvo contributor: fullname: Potočnik – volume: 49 start-page: 24 year: 2016 ident: 10.3168/jds.2019-17264_bib38 article-title: Effect of processing on conformational changes of food proteins related to allergenicity publication-title: Trends Food Sci. Technol. doi: 10.1016/j.tifs.2016.01.001 contributor: fullname: Rahaman – volume: 8 start-page: 249 year: 2008 ident: 10.3168/jds.2019-17264_bib28 article-title: The impact of processing on allergenicity of food publication-title: Curr. Opin. Allergy Clin. Immunol. doi: 10.1097/ACI.0b013e3282ffb123 contributor: fullname: Mills – volume: 67 start-page: 1171 year: 2012 ident: 10.3168/jds.2019-17264_bib34 article-title: In search of a tolerance-induction strategy for cow's milk allergies: Significant reduction of beta-lactoglobulin allergenicity via transglutaminase/cysteine polymerization: Allergoid generation by polymerization publication-title: Clinics (São Paulo) doi: 10.6061/clinics/2012(10)09 contributor: fullname: Olivier – volume: 107 start-page: 891 year: 2001 ident: 10.3168/jds.2019-17264_bib40 article-title: Utility of food-specific IgE concentrations in predicting symptomatic food allergy publication-title: J. Allergy Clin. Immunol. doi: 10.1067/mai.2001.114708 contributor: fullname: Sampson – volume: 72 start-page: 248 year: 1976 ident: 10.3168/jds.2019-17264_bib2 article-title: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding publication-title: Anal. Biochem. doi: 10.1016/0003-2697(76)90527-3 contributor: fullname: Bradford – volume: 48 start-page: 434 year: 2004 ident: 10.3168/jds.2019-17264_bib36 article-title: Evaluation of the potential allergenicity of the enzyme microbial transglutaminase using the 2001 FAO/WHO decision tree publication-title: Mol. Nutr. Food Res. doi: 10.1002/mnfr.200400014 contributor: fullname: Pedersen – volume: 42 start-page: 899 year: 2009 ident: 10.3168/jds.2019-17264_bib17 article-title: Functional properties of milk proteins as affected by enzymatic oligomerisation publication-title: Food Res. Int. doi: 10.1016/j.foodres.2009.04.022 contributor: fullname: Hiller – volume: 66 start-page: 22 year: 2014 ident: 10.3168/jds.2019-17264_bib18 article-title: Cow's milk allergy: From allergens to new forms of diagnosis, therapy and prevention publication-title: Methods doi: 10.1016/j.ymeth.2013.08.005 contributor: fullname: Hochwallner – volume: 4 start-page: 2496 year: 2004 ident: 10.3168/jds.2019-17264_bib31 article-title: Proteomic tools to characterize the protein fraction of Equidae milk publication-title: Proteomics doi: 10.1002/pmic.200300765 contributor: fullname: Miranda – volume: 7 start-page: 1 year: 2009 ident: 10.3168/jds.2019-17264_bib41 article-title: Should digestion assays be used to estimate persistence of potential allergens in tests for safety of novel food proteins? publication-title: Clin. Mol. Allergy doi: 10.1186/1476-7961-7-1 contributor: fullname: Schnell – volume: 17 start-page: 3 year: 2007 ident: 10.3168/jds.2019-17264_bib1 article-title: Improvement of enzymatic cross-linking of casein micelles with transglutaminase by glutathione addition publication-title: Int. Dairy J. doi: 10.1016/j.idairyj.2006.01.007 contributor: fullname: Bönisch – volume: 21 start-page: 1 issue: Suppl. 21 year: 2010 ident: 10.3168/jds.2019-17264_bib9 article-title: World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guidelines publication-title: Pediatr. Allergy Immunol. contributor: fullname: Fiocchi – volume: 53 start-page: 959 year: 2009 ident: 10.3168/jds.2019-17264_bib35 article-title: Aspects of food processing and its effect on allergen structure publication-title: Mol. Nutr. Food Res. doi: 10.1002/mnfr.200800187 contributor: fullname: Paschke – volume: 25 start-page: 123 year: 2012 ident: 10.3168/jds.2019-17264_bib45 article-title: Effect of polymerization with transglutaminase on in vitro digestion and antigenicity of β-lactoglobulin publication-title: Int. Dairy J. doi: 10.1016/j.idairyj.2012.02.007 contributor: fullname: Villas-Boas – volume: 72 start-page: 184 year: 2015 ident: 10.3168/jds.2019-17264_bib12 article-title: Mare's and cow's milk: Promote similar metabolic effects and expression of innate markers in Caco-2 cells? publication-title: Food Res. Int. doi: 10.1016/j.foodres.2015.04.001 contributor: fullname: Fotschki – volume: 126 start-page: 72 year: 2016 ident: 10.3168/jds.2019-17264_bib26 article-title: A simultaneous two-colour detection method of human IgG- and IgE-reactive proteins from lactic acid bacteria publication-title: J. Microbiol. Methods doi: 10.1016/j.mimet.2016.05.007 contributor: fullname: Markiewicz – volume: 54 start-page: 1273 year: 2010 ident: 10.3168/jds.2019-17264_bib42 article-title: Digestibility and allergenicity assessment of enzymatically crosslinked β-casein publication-title: Mol. Nutr. Food Res. doi: 10.1002/mnfr.200900184 contributor: fullname: Stanic – volume: 6 start-page: 16 year: 2012 ident: 10.3168/jds.2019-17264_bib5 article-title: Charakterystyka i właściwości prozdrowotne mleka klaczy (Characteristics and salubrious properties of mare milk) publication-title: Nauka Przyr. Tech. contributor: fullname: Danków – volume: 99 start-page: 9395 year: 2016 ident: 10.3168/jds.2019-17264_bib11 article-title: Immune-modulating properties of horse milk administered to mice sensitized to cow milk publication-title: J. Dairy Sci. doi: 10.3168/jds.2016-11499 contributor: fullname: Fotschki – volume: 55 start-page: 235 year: 2000 ident: 10.3168/jds.2019-17264_bib20 article-title: Why are some proteins allergens? publication-title: Toxicol. Sci. doi: 10.1093/toxsci/55.2.235 contributor: fullname: Huby – volume: 59 start-page: 159 year: 2019 ident: 10.3168/jds.2019-17264_bib14 article-title: Altering allergenicity of cow's milk by food processing for applications in infant formula publication-title: Crit. Rev. Food Sci. Nutr. doi: 10.1080/10408398.2017.1363156 contributor: fullname: Golkar |
SSID | ssj0021205 |
Score | 2.4413624 |
Snippet | Horse milk is a valuable raw material and a very attractive alternative for scientific research to address the issue of cow milk (CM) allergy due to its... |
SourceID | proquest crossref pubmed elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 2153 |
SubjectTerms | cow milk protein allergy horse milk microbial transglutaminase simulated gastrointestinal digestion |
Title | Microbial transglutaminase alters the immunogenic potential and cross-reactivity of horse and cow milk proteins |
URI | https://dx.doi.org/10.3168/jds.2019-17264 https://www.ncbi.nlm.nih.gov/pubmed/31928755 https://search.proquest.com/docview/2338070890 |
Volume | 103 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT-MwEB5BuSyHFeyLLg8ZCYmT1fiRtD4WtAhtYQ8IFm6R49oQ2E2qNhV_nxknRdpDL3tJpMSjWDPjecTjbwBO0KUVBGzDbeI018E4btHq8TDSwaHQrbD0H_L6V3Z5p38-pA8bcL46C0NllZ3tb216tNbdk0HHzcGsLOmMr5SoovFCANibsCVpm6kHW-Oz35Or97xLyLaSkQrXiaDFbqSOTYPnKUF2C8PRj2d6nW9aF3tGH3SxAx-74JGN2_ntwoavPsH2-HHeAWj4z1BflxFaCYc15IYeUbMslbssPIs74wuGIR8r6VhIjcpTOjarGyoZQgpbTVmcGsdQ0rV9JVgd2FM9J3J6W7-yv-WfFxbxHcpq8QXuLn7cnl_yrqkCd2qkG-6p0YXyw2DsULmpVC4zQjmvpU-HQjqfyBCsJ1R2IzOVCZd5IQvhcOkbk3r1FXpVXfk9YGpoQqLUNCPAGVc4Y5PCaqfTJIhgR64Ppyt25rMWOyPHnIMYnyPjc2J8HhnfB7Hidv6P9HM07GtpjldiyXFJ0D6HrXy9xDGKUPSTkUn68K2V1_v30eJgjpim3__ji_vwQVK2HSvQDqDXzJf-EEOSpjjqVI7uk5v7yRuciOEZ |
link.rule.ids | 315,786,790,27600,27955,27956,45696 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV07b9swED6kydBmKJq-4jZNWaBAJ8LiQ7I5ukEDt7EzJUU2gqLJVG0iGbaC_P3cUXKADF66aJB4IHF3vId4_A7gK7q0koBtuMu85joazx1aPR7HOnoUuhOO_kPOz4vppf51lV_twMnmLgyVVfa2v7PpyVr3b4Y9N4fLqqI7vlKiiqYHAWA_gz2MBgyq-d7k---z2WPeJWRXyUiF60TQYTdSx6bh3wVBdgvD0Y8Xeptv2hZ7Jh90-gpe9sEjm3TrO4CdUL-G_cn1qgfQCG-gmVcJWgmHteSGrlGzHJW7rANLJ-NrhiEfq-haSIPKU3m2bFoqGUIKVy9YWhrHUNJ3fSVYE9mfZkXk9LW5Z7fVzT-W8B2qev0WLk9_XJxMed9UgXs11i0P1OhChVE0bqT8QipfGKF80DLkIyF9yGSMLhAqu5GFKoQvgpCl8Lj1jcmDege7dVOHQ2BqZGKm1KIgwBlfeuOy0mmv8yyK6MZ-AN827LTLDjvDYs5BjLfIeEuMt4nxAxAbbtsn0rdo2LfSfNmIxeKWoHMOV4fmDscoQtHPxiYbwPtOXo_zo8XBHDHPP_zHjJ_h-fRiPrOzn-dnH-GFpMw7VaMdwW67ugufMDxpy-Ne_R4AWy_ibw |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Microbial+transglutaminase+alters+the+immunogenic+potential+and+cross-reactivity+of+horse+and+cow+milk+proteins&rft.jtitle=Journal+of+dairy+science&rft.au=Fotschki%2C+J.&rft.au=Wr%C3%B3blewska%2C+B.&rft.au=Fotschki%2C+B.&rft.au=Kalicki%2C+B.&rft.date=2020-03-01&rft.issn=0022-0302&rft.volume=103&rft.issue=3&rft.spage=2153&rft.epage=2166&rft_id=info:doi/10.3168%2Fjds.2019-17264&rft.externalDBID=n%2Fa&rft.externalDocID=10_3168_jds_2019_17264 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-0302&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-0302&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-0302&client=summon |